Dehydrocurvularin is a potent antineoplastic agent irreversibly blocking ATP-citrate lyase: evidence from chemoproteomics - Deng, Zhangshuang; Wong, Nai-Kei; Guo, Zhiyong; Zou, Kun; Xiao, Youli; Zhou, Yiqing (Chemical communications (Cambridge, England), 2019)
Keywords: antineoplastic agents; Antineoplastic Agents - pharmacology; ATP Citrate (pro-S)-Lyase - antagonists & inhibitors; ATP Citrate (pro-S)-Lyase - metabolism; ATP citrate synthase; Cell Proliferation - drug effects; chemical reactions; dehydrocurvularin; Enzyme Inhibitors - pharmacology; HeLa Cells; Humans; mechanism of action; Proteomics; Zearalenone - analogs & derivatives; Zearalenone - pharmacology