Endosomal pH is an evolutionarily conserved driver of phenotypic plasticity in colorectal cancer - Prasad, Hari; BV, Harshavardhan; Subbalakshmi, Ayalur Raghu; Mandal, Susmita; Jolly, Mohit Kumar; Visweswariah, Sandhya S. (NPJ systems biology and applications, 2024)
Keywords: 631/114; 631/67; Bioinformatics; Biomedical and Life Sciences; Calcium signalling; Cancer; Cell Line, Tumor; Cell migration; Cell Movement - genetics; Cell Movement - physiology; Cell proliferation; Cell survival; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - genetics; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Ectopic expression; Endosomes - metabolism; Epithelial-Mesenchymal Transition - genetics; Gene Expression Regulation, Neoplastic - genetics; Humans; Hydrogen-Ion Concentration; Hypoxia; Life Sciences; Metastases; Metastasis; Na+/H+-exchanging ATPase; pH effects; Phenotype; Phenotypes; Phenotypic plasticity; Sequence analysis; Sodium-Hydrogen Exchangers - genetics; Sodium-Hydrogen Exchangers - metabolism; Systems Biology; Therapeutic targets