Long Noncoding RNA in Hematopoiesis and Immunity

• Published in: Immunity (Cambridge, Mass.) Vol. 42; no. 5; pp. 792 - 804
• Main Authors: Satpathy, Ansuman T., Chang, Howard Y.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.05.2015; Elsevier Limited
• Subjects: Binding sites; Deoxyribonucleic acid; DNA; Flow cytometry; Gene Expression Regulation - immunology; Genes; Genomes; Genomics; Hematopoiesis - immunology; Humans; Immune system; Immunity; Proteins; RNA, Long Noncoding - immunology; Studies

Dynamic gene expression during cellular differentiation is tightly coordinated by transcriptional and post-transcriptional mechanisms. An emerging theme is the central role of long noncoding RNAs (lncRNAs) in the regulation of this specificity. Recent advances demonstrate that lncRNAs are expressed...