Familial clustering of dysbiotic oral and fecal microbiomes in juvenile dermatomyositis

Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequ...

Full description

Saved in:
Bibliographic Details
Published inScientific reports Vol. 14; no. 1; pp. 16158 - 13
Main Authors Koester, Sean T., Chow, Albert, Pepper-Tunick, Evan, Lee, Peggy, Eckert, Mary, Brenchley, Laurie, Gardner, Pamela, Song, Hyun Jung, Li, Naisi, Schiffenbauer, Adam, Volochayev, Rita, Bayat, Nastaran, McLean, Jeffrey S., Rider, Lisa G., Shenoi, Susan, Stevens, Anne M., Dey, Neelendu
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 12.07.2024
Nature Publishing Group
Nature Portfolio
Subjects
631/326/2565/2134
692/4023/1670/427
Adolescent
Adult
Child
Child, Preschool
Children
Community structure
Dermatomyositis
Dermatomyositis - genetics
Dermatomyositis - microbiology
Dysbiosis - microbiology
Families & family life
Feces
Feces - microbiology
Female
Gastrointestinal Microbiome - genetics
Humanities and Social Sciences
Humans
Immunomodulation
Intestinal microflora
Male
Microbiomes
Microbiota - genetics
Mouth - microbiology
multidisciplinary
Observational studies
Oral cavity
Prospective Studies
RNA, Ribosomal, 16S - genetics
rRNA 16S
Saliva
Saliva - microbiology
Science
Science (multidisciplinary)
Siblings
Online AccessGet full text

Cover

Abstract Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands ( n  = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members ( n  = 27 siblings, n  = 26 mothers, and n  = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.
AbstractList Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands (n = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members (n = 27 siblings, n = 26 mothers, and n = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.
Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands ( n  = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members ( n  = 27 siblings, n  = 26 mothers, and n  = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.
Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands (n = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members (n = 27 siblings, n = 26 mothers, and n = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands (n = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members (n = 27 siblings, n = 26 mothers, and n = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.
Abstract Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM is associated with discrete oral and gut microbiome signatures. We generated 16S rRNA sequencing data from fecal, saliva, supragingival, and subgingival plaque samples from JDM probands (n = 28). To control for genetic and environmental determinants of microbiome community structure, we also profiled microbiomes of unaffected family members (n = 27 siblings, n = 26 mothers, and n = 17 fathers). Sample type (oral-vs-fecal) and nuclear family unit were the predominant variables explaining variance in microbiome diversity, more so than having a diagnosis of JDM. The oral and gut microbiomes of JDM probands were more similar to their own unaffected siblings than they were to the microbiomes of other JDM probands. In a sibling-paired within-family analysis, several potentially immunomodulatory bacterial taxa were differentially abundant in the microbiomes of JDM probands compared to their unaffected siblings, including Faecalibacterium (gut) and Streptococcus (oral cavity). While microbiome features of JDM are often shared by unaffected family members, the loss or gain of specific fecal and oral bacteria may play a role in disease pathogenesis or be secondary to immune dysfunction in susceptible individuals.
ArticleNumber 16158
Author Koester, Sean T.
McLean, Jeffrey S.
Rider, Lisa G.
Gardner, Pamela
Song, Hyun Jung
Volochayev, Rita
Chow, Albert
Pepper-Tunick, Evan
Schiffenbauer, Adam
Li, Naisi
Lee, Peggy
Dey, Neelendu
Eckert, Mary
Stevens, Anne M.
Shenoi, Susan
Brenchley, Laurie
Bayat, Nastaran
Author_xml – sequence: 1
  givenname: Sean T.
  surname: Koester
  fullname: Koester, Sean T.
  organization: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, University of Kansas School of Medicine
– sequence: 2
  givenname: Albert
  surname: Chow
  fullname: Chow, Albert
  organization: Department of Pediatrics, Division of Rheumatology, University of Washington, Loma Linda University
– sequence: 3
  givenname: Evan
  surname: Pepper-Tunick
  fullname: Pepper-Tunick, Evan
  organization: Molecular Engineering and Sciences Institute, University of Washington
– sequence: 4
  givenname: Peggy
  surname: Lee
  fullname: Lee, Peggy
  organization: School of Dentistry, University of Washington
– sequence: 5
  givenname: Mary
  surname: Eckert
  fullname: Eckert, Mary
  organization: Center for Clinical and Translational Research, Seattle Children’s Research Institute, Center for Immunity and Immunotherapies, Seattle Children’s Research Institute
– sequence: 6
  givenname: Laurie
  surname: Brenchley
  fullname: Brenchley, Laurie
  organization: Office of the Clinical Director, NIDCR, National Institutes of Health
– sequence: 7
  givenname: Pamela
  surname: Gardner
  fullname: Gardner, Pamela
  organization: Office of the Clinical Director, NIDCR, National Institutes of Health, Oral Oncology at BC Cancer
– sequence: 8
  givenname: Hyun Jung
  surname: Song
  fullname: Song, Hyun Jung
  organization: School of Dentistry, University of Washington
– sequence: 9
  givenname: Naisi
  surname: Li
  fullname: Li, Naisi
  organization: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center
– sequence: 10
  givenname: Adam
  surname: Schiffenbauer
  fullname: Schiffenbauer, Adam
  organization: Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health
– sequence: 11
  givenname: Rita
  surname: Volochayev
  fullname: Volochayev, Rita
  organization: Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health
– sequence: 12
  givenname: Nastaran
  surname: Bayat
  fullname: Bayat, Nastaran
  organization: Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Social and Scientific Systems, Inc., A DLH Holdings Corp. Company
– sequence: 13
  givenname: Jeffrey S.
  surname: McLean
  fullname: McLean, Jeffrey S.
  organization: Department of Periodontics, University of Washington
– sequence: 14
  givenname: Lisa G.
  surname: Rider
  fullname: Rider, Lisa G.
  organization: Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health
– sequence: 15
  givenname: Susan
  surname: Shenoi
  fullname: Shenoi, Susan
  organization: Department of Pediatrics, Division of Rheumatology, University of Washington, Center for Clinical and Translational Research, Seattle Children’s Research Institute
– sequence: 16
  givenname: Anne M.
  surname: Stevens
  fullname: Stevens, Anne M.
  organization: Department of Pediatrics, Division of Rheumatology, University of Washington, Center for Clinical and Translational Research, Seattle Children’s Research Institute, Janssen, a Wholly Owned Subsidiary of Johnson & Johnson
– sequence: 17
  givenname: Neelendu
  surname: Dey
  fullname: Dey, Neelendu
  email: ndey@fredhutch.org
  organization: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Department of Medicine, Division of Gastroenterology, University of Washington, Microbiome Research Initiative, Fred Hutchinson Cancer Center
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38997299$$D View this record in MEDLINE/PubMed
BookMark eNp9kctu1TAQhi1URC_0BVigSGzYBHy_LFFFaaVKbEAsLcceVz5K4oOdIJ23r3tSCmKBNx55vn_GM_85OpnzDAi9IfgDwUx_rJwIo3tMeS8xpaLHL9AZxVz0lFF68ld8ii5r3eF2BDWcmFfolGljFDXmDP24dlMakxs7P651gZLm-y7HLhzqkPKSfJdLS7o5dBF8i6bkS26pCWqX5m63_oI5jdAFKJNb8nTINS2pvkYvoxsrXD7dF-j79edvVzf93dcvt1ef7nrPmVx6HQiXBpsYFHgi1WCGwMGzyLzkFNwwOEGJFljKSGTU3A9aBRE98MbgyC7Q7VY3ZLez-5ImVw42u2SPD7ncW1faGCNYypqOkAEbJTkoGLQgQXClGFNaCNJqvd9q7Uv-uUJd7JSqh3F0M-S1WoaV0UJSYhr67h90l9cyt0mPlCQMM9mot0_UOkwQnr_3e_0NoBvQdlprgfiMEGwfbbabzbbZbI82W9xEbBPV_aNbUP70_o_qAX7LqJM
Cites_doi 10.1053/j.gastro.2020.11.050
10.1128/AEM.71.12.8228-8235.2005
10.1002/art.34539
10.1186/s42358-018-0024-x
10.3389/fcimb.2021.629723
10.1177/0961203313501401
10.1002/ibd.20903
10.1038/nature11053
10.1186/1471-230X-13-131
10.1177/00220345000790021301
10.1016/j.chom.2019.05.003
10.3389/fmicb.2019.01746
10.1056/NEJM197502132920706
10.3389/fmicb.2019.02407
10.1038/s41587-019-0209-9
10.1038/s41467-022-33071-9
10.1016/S0140-6736(08)60955-1
10.1186/s13073-016-0299-7
10.1016/j.rdc.2013.06.001
10.1016/j.semarthrit.2020.01.002
10.1016/j.ebiom.2023.104654
10.1073/pnas.0804812105
10.1016/j.cell.2015.08.059
10.1073/pnas.2114152118
10.12998/wjcc.v7.i18.2734
10.1038/ajg.2012.335
10.3389/fmicb.2022.799602
10.1186/s12864-020-6703-0
10.1097/MD.0b013e31827f264d
10.1002/art.10566
10.1186/s12920-023-01449-3
10.7554/eLife.00458
10.1186/s12969-019-0387-5
10.1056/NEJM197502202920807
10.1016/j.chom.2021.02.021
10.3390/ijms19102938
10.1016/j.chom.2020.12.008
10.1128/JCM.01396-12
10.1371/journal.pone.0218319
10.7554/eLife.46923
10.1038/nmeth.3869
10.1007/s00784-016-2035-5
10.1016/j.isci.2021.102508
10.1046/j.1365-2958.2001.02448.x
10.3389/fimmu.2020.597966
10.1038/srep23561
10.1002/art.41780
10.55563/clinexprheumatol/56ilob
10.1097/MIB.0000000000000332
10.1111/j.1348-0421.1998.tb02328.x
10.1371/journal.pone.0248730
10.1038/s41586-018-0620-2
10.3389/fcimb.2020.602239
10.1038/ismej.2017.119
10.1002/art.40405
10.3389/fped.2021.626232
10.1002/art.11122
10.1186/s40360-021-00536-4
10.1038/s41598-018-35473-6
10.1128/IAI.68.6.3140-3146.2000
10.1371/journal.pcbi.1003531
10.1093/rheumatology/keq189
10.1038/s41598-018-22491-7
10.1214/19-AOAS1283
10.1128/mSystems.00117-19
ContentType Journal Article
Copyright The Author(s) 2024
2024. The Author(s).
The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2024
– notice: 2024. The Author(s).
– notice: The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7X7
7XB
88A
88E
88I
8FE
8FH
8FI
8FJ
8FK
ABUWG
AEUYN
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
LK8
M0S
M1P
M2P
M7P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
Q9U
7X8
DOA
DOI 10.1038/s41598-024-60225-0
DatabaseName SpringerOpen Free (Free internet resource, activated by CARLI)
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Biology Database (Alumni Edition)
Medical Database (Alumni Edition)
Science Database (Alumni Edition)
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
Proquest Central
Natural Science Collection
ProQuest One
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
ProQuest Health & Medical Collection
Medical Database
Science Database
Biological Science Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest Central Basic
MEDLINE - Academic
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Central China
ProQuest Biology Journals (Alumni Edition)
ProQuest Central
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Health & Medical Research Collection
Biological Science Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Science Journals (Alumni Edition)
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Science Journals
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE
Publicly Available Content Database
CrossRef
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: C6C
  name: Springer Nature OA Free Journals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: DOA
  name: Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 3
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 4
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 5
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 2045-2322
EndPage 13
ExternalDocumentID oai_doaj_org_article_235fc11b09764e7eb851d54773378551
38997299
10_1038_s41598_024_60225_0
Genre Multicenter Study
Journal Article
Observational Study
GrantInformation_xml – fundername: Childhood Arthritis and Rheumatology Research Alliance
– fundername: National Institute of Environmental Health Sciences
  grantid: HHSN2732016000021
– fundername: National Institutes of Health
  grantid: ZIAES101074
– fundername: National Institute of Diabetes and Digestive and Kidney Diseases
  grantid: DK111941
– fundername: Cure JM Foundation
– fundername: NCI NIH HHS
  grantid: U54 CA274374
– fundername: Intramural NIH HHS
  grantid: ZIA ES101074
– fundername: NIDDK NIH HHS
  grantid: DK111941
– fundername: NIH HHS
  grantid: ZIAES101074
– fundername: NIDDK NIH HHS
  grantid: K08 DK111941
– fundername: NIEHS NIH HHS
  grantid: HHSN2732016000021
GroupedDBID 0R~
3V.
4.4
53G
5VS
7X7
88A
88E
88I
8FE
8FH
8FI
8FJ
AAFWJ
AAJSJ
AAKDD
ABDBF
ABUWG
ACGFS
ACSMW
ACUHS
ADBBV
ADRAZ
AENEX
AEUYN
AFKRA
AJTQC
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
AZQEC
BAWUL
BBNVY
BCNDV
BENPR
BHPHI
BPHCQ
BVXVI
C6C
CCPQU
DIK
DWQXO
EBD
EBLON
EBS
ESX
FYUFA
GNUQQ
GROUPED_DOAJ
GX1
HCIFZ
HH5
HMCUK
HYE
KQ8
LK8
M0L
M1P
M2P
M48
M7P
M~E
NAO
OK1
PIMPY
PQQKQ
PROAC
PSQYO
RNT
RNTTT
RPM
SNYQT
UKHRP
AASML
AAYXX
AFPKN
CITATION
PHGZM
PHGZT
CGR
CUY
CVF
ECM
EIF
NPM
PJZUB
PPXIY
PQGLB
7XB
8FK
AARCD
K9.
PKEHL
PQEST
PQUKI
PRINS
Q9U
7X8
PUEGO
ID FETCH-LOGICAL-c436t-8d146909fd7ec167b9bd4ec3f3c642eabba52185066f16f84cb87d5fce43f30f3
IEDL.DBID 7X7
ISSN 2045-2322
IngestDate Wed Aug 27 00:31:51 EDT 2025
Thu Jul 10 22:01:45 EDT 2025
Wed Aug 13 11:12:00 EDT 2025
Wed Jul 23 01:46:42 EDT 2025
Tue Jul 01 01:02:09 EDT 2025
Fri Feb 21 02:39:46 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
License 2024. The Author(s).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c436t-8d146909fd7ec167b9bd4ec3f3c642eabba52185066f16f84cb87d5fce43f30f3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ObjectType-Undefined-3
OpenAccessLink https://www.proquest.com/docview/3079613036?pq-origsite=%requestingapplication%
PMID 38997299
PQID 3079613036
PQPubID 2041939
PageCount 13
ParticipantIDs doaj_primary_oai_doaj_org_article_235fc11b09764e7eb851d54773378551
proquest_miscellaneous_3079856219
proquest_journals_3079613036
pubmed_primary_38997299
crossref_primary_10_1038_s41598_024_60225_0
springer_journals_10_1038_s41598_024_60225_0
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2024-07-12
PublicationDateYYYYMMDD 2024-07-12
PublicationDate_xml – month: 07
  year: 2024
  text: 2024-07-12
  day: 12
PublicationDecade 2020
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle Scientific reports
PublicationTitleAbbrev Sci Rep
PublicationTitleAlternate Sci Rep
PublicationYear 2024
Publisher Nature Publishing Group UK
Nature Publishing Group
Nature Portfolio
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
– name: Nature Portfolio
References Jardou, Provost, Brossier, Pinault, Sauvage, Lawson (CR52) 2021; 22
Li, Koester, Lachance, Dutta, Cui, Dey (CR59) 2021; 24
Yatsunenko, Rey, Manary, Trehan, Dominguez-Bello, Contreras (CR47) 2012; 486
Huang, Inoue, Leone, Dalal, Touw, Wang (CR51) 2015; 21
Chen, Zhao, Li, Yang, Wang, Wang (CR34) 2018; 8
Feldman, Rider, Reed, Pachman (CR2) 2008; 371
Callahan, McMurdie, Rosen, Han, Johnson, Holmes (CR61) 2016; 13
Massa, Costouros, Mazzoli, De Benedetti, La Cava, Le (CR31) 2002; 46
Vatanen, Franzosa, Schwager, Tripathi, Arthur, Vehik (CR25) 2018; 562
Ruff, Dehner, Kim, Pagovich, Aguiar, Yu (CR26) 2019; 26
Mendez, Lipton, Ramsey-Goldman, Roettcher, Bowyer, Dyer (CR1) 2003; 49
Grevich, Lee, Leroux, Ringold, Darveau, Henstorf (CR41) 2019; 17
Maeda, Okamoto, Kondo, Ishikawa, Osada, Tsurumoto (CR46) 1998; 42
Song, Lauber, Costello, Lozupone, Humphrey, Berg-Lyons (CR48) 2013; 2
McLaren, Willis, Callahan (CR68) 2019; 8
Willis (CR65) 2019; 10
Rashidi, Ebadi, Weisdorf, Costalonga, Staley (CR32) 2021; 118
Dong, Wang, Li, Ma, Zhong, Wei (CR22) 2019; 7
Bohan, Peter (CR53) 1975; 292
Shah, Mamyrova, Targoff, Huber, Malley, Rice (CR66) 2013; 92
McMurdie, Holmes (CR64) 2014; 10
de Paiva, Jones, Stern, Bian, Moore, Corbiere (CR20) 2016; 6
Dey, Wagner, Blanton, Cheng, Fontana, Haque (CR57) 2015; 163
Dey, Soergel, Repo, Brenner (CR5) 2013; 13
Wu, Zegarra-Ruiz, Diehl (CR8) 2020; 11
Bae, Dong, Wang, Lagishetty, Katzka, Jacobs (CR24) 2022; 1
Bohan, Peter (CR54) 1975; 292
Wang, Zhang, Chang, Qiao, Wang, Li (CR27) 2022; 13
Gill, Asquith, Brooks, Rosenbaum, Colbert (CR49) 2018; 70
Sokol, Seksik, Furet, Firmesse, Nion-Larmurier, Beaugerie (CR17) 2009; 15
Vieira, Pagovich, Kriegel (CR6) 2014; 23
Rashidi, Koyama, Dey, McLean, Hill (CR33) 2023; 16
Rider, Werth, Huber, Alexanderson, Rao, Ruperto (CR55) 2011; 63
McCann, Livermore, Wilkinson, Wedderburn (CR4) 2022; 40
Chen, Wright, Davis, Jeraldo, Marietta, Murray (CR15) 2016; 8
Nayak, Alexander, Deshpande, Stapleton-Gray, Rimal, Patterson (CR50) 2021; 29
Bergmann, Rohde, Chhatwal, Hammerschmidt (CR37) 2001; 40
Macuch, Tanner (CR38) 2000; 79
Sokol, Pigneur, Watterlot, Lakhdari, Bermúdez-Humarán, Gratadoux (CR16) 2008; 105
Mori, Orena, Cultrera, Barbieri, Albertini, Ranzani (CR12) 2019; 10
Kindgren, Ahrens, Triplett, Ludvigsson (CR30) 2023; 93
Kozu, Silva, Aikawa, Pereira, Sallum, Savioli (CR36) 2018; 58
CR11
CR10
Rusthen, Kristoffersen, Young, Galtung, Petrovski, Palm (CR44) 2019; 14
Ling, Lu, Zhao, Lulla, Plantinga, Fu (CR14) 2022; 13
Hansen, Russell, Reiff, Louis, McIntosh, Berry (CR19) 2012; 107
Picchianti-Diamanti, Panebianco, Salemi, Sorgi, Di Rosa, Tropea (CR21) 2018; 19
Yasunaga, Takeshita, Shibata, Furuta, Shimazaki, Akifusa (CR42) 2017; 21
Scher, Ubeda, Equinda, Khanin, Buischi, Viale (CR40) 2012; 64
Qian, Liu, Ye, Zheng, Lv, Mo (CR23) 2020; 21
Lenartova, Tesinska, Janatova, Hrebicek, Mysak, Janata (CR43) 2021; 11
Roswall, Olsson, Kovatcheva-Datchary, Nilsson, Tremaroli, Simon (CR13) 2021; 29
Zhuang, Liu, Zhan, Tian, Li, Mao (CR18) 2021; 9
Han, Shi, Huang, Kinder Haake, Park, Kuramitsu (CR35) 2000; 68
Franzosa, Sirota-Madi, Avila-Pacheco, Fornelos, Haiser, Reinker (CR7) 2018; 1
Ahmed, Chen, Werth (CR56) 2020; 50
Bolyen, Rideout, Dillon, Bokulich, Abnet, Al-Ghalith (CR62) 2019; 37
CR67
Savioli, Silva, Fabri, Kozu, Campos, Bonfá (CR9) 2010; 49
Rider, Katz, Jones (CR3) 2013; 39
Kim, Tarassishin, Eisele, Barre, Nair, Rendon (CR29) 2021; 160
Kroese, Brandt, Buijs, Crielaard, Lobbezoo, Loos (CR45) 2021; 73
Lozupone, Knight (CR63) 2005; 71
Koester, Li, Lachance, Morella, Dey (CR58) 2021; 16
Kaakoush, Day, Huinao, Leach, Lemberg, Dowd (CR28) 2012; 50
Frid, Baraniya, Halbig, Rypdal, Songstad, Rosèn (CR39) 2020; 10
Callahan, McMurdie, Holmes (CR60) 2017; 11
A Rashidi (60225_CR32) 2021; 118
N Dey (60225_CR5) 2013; 13
E Bolyen (60225_CR62) 2019; 37
60225_CR10
60225_CR11
T Gill (60225_CR49) 2018; 70
M Jardou (60225_CR52) 2021; 22
A Bohan (60225_CR53) 1975; 292
Q Wang (60225_CR27) 2022; 13
BJ Callahan (60225_CR61) 2016; 13
BJ Callahan (60225_CR60) 2017; 11
A Picchianti-Diamanti (60225_CR21) 2018; 19
WE Ruff (60225_CR26) 2019; 26
NO Kaakoush (60225_CR28) 2012; 50
BM Feldman (60225_CR2) 2008; 371
S Bergmann (60225_CR37) 2001; 40
S Grevich (60225_CR41) 2019; 17
SJ Song (60225_CR48) 2013; 2
R Hansen (60225_CR19) 2012; 107
M Shah (60225_CR66) 2013; 92
KT Kozu (60225_CR36) 2018; 58
H Yasunaga (60225_CR42) 2017; 21
N Maeda (60225_CR46) 1998; 42
G Mori (60225_CR12) 2019; 10
E Kindgren (60225_CR30) 2023; 93
A Rashidi (60225_CR33) 2023; 16
H Sokol (60225_CR16) 2008; 105
JU Scher (60225_CR40) 2012; 64
SS Bae (60225_CR24) 2022; 1
60225_CR67
SM Vieira (60225_CR6) 2014; 23
CS de Paiva (60225_CR20) 2016; 6
C Savioli (60225_CR9) 2010; 49
P Frid (60225_CR39) 2020; 10
T Vatanen (60225_CR25) 2018; 562
LG Rider (60225_CR3) 2013; 39
AD Willis (60225_CR65) 2019; 10
WJH Wu (60225_CR8) 2020; 11
H Sokol (60225_CR17) 2009; 15
T Yatsunenko (60225_CR47) 2012; 486
RR Nayak (60225_CR50) 2021; 29
X Zhuang (60225_CR18) 2021; 9
JM Kroese (60225_CR45) 2021; 73
X Qian (60225_CR23) 2020; 21
B Chen (60225_CR34) 2018; 8
EP Mendez (60225_CR1) 2003; 49
M Massa (60225_CR31) 2002; 46
EA Franzosa (60225_CR7) 2018; 1
PJ McMurdie (60225_CR64) 2014; 10
YW Han (60225_CR35) 2000; 68
A Bohan (60225_CR54) 1975; 292
LJ McCann (60225_CR4) 2022; 40
M Lenartova (60225_CR43) 2021; 11
N Dey (60225_CR57) 2015; 163
S Rusthen (60225_CR44) 2019; 14
EY Huang (60225_CR51) 2015; 21
W Ling (60225_CR14) 2022; 13
S Ahmed (60225_CR56) 2020; 50
J Chen (60225_CR15) 2016; 8
PJ Macuch (60225_CR38) 2000; 79
ES Kim (60225_CR29) 2021; 160
MR McLaren (60225_CR68) 2019; 8
N Li (60225_CR59) 2021; 24
J Roswall (60225_CR13) 2021; 29
ST Koester (60225_CR58) 2021; 16
Y-Q Dong (60225_CR22) 2019; 7
LG Rider (60225_CR55) 2011; 63
C Lozupone (60225_CR63) 2005; 71
References_xml – volume: 160
  start-page: 1118
  year: 2021
  end-page: 1130.e3
  ident: CR29
  article-title: Longitudinal changes in fecal calprotectin levels among pregnant women with and without inflammatory bowel disease and their babies
  publication-title: Gastroenterology.
  doi: 10.1053/j.gastro.2020.11.050
– volume: 71
  start-page: 8228
  year: 2005
  end-page: 8235
  ident: CR63
  article-title: UniFrac: A new phylogenetic method for comparing microbial communities
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.71.12.8228-8235.2005
– volume: 64
  start-page: 3083
  year: 2012
  end-page: 3094
  ident: CR40
  article-title: Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.34539
– volume: 58
  start-page: 28
  year: 2018
  ident: CR36
  article-title: Juvenile dermatomyositis: Is periodontal disease associated with dyslipidemia?
  publication-title: Adv. Rheumatol.
  doi: 10.1186/s42358-018-0024-x
– volume: 11
  year: 2021
  ident: CR43
  article-title: The oral microbiome in periodontal health
  publication-title: Front. Cell Infect. Microbiol.
  doi: 10.3389/fcimb.2021.629723
– volume: 23
  start-page: 518
  year: 2014
  end-page: 526
  ident: CR6
  article-title: Diet, microbiota and autoimmune diseases
  publication-title: Lupus.
  doi: 10.1177/0961203313501401
– volume: 15
  start-page: 1183
  year: 2009
  end-page: 1189
  ident: CR17
  article-title: Low counts of Faecalibacterium prausnitzii in colitis microbiota
  publication-title: Inflamm. Bowel Dis.
  doi: 10.1002/ibd.20903
– volume: 486
  start-page: 222
  year: 2012
  end-page: 227
  ident: CR47
  article-title: Human gut microbiome viewed across age and geography
  publication-title: Nature.
  doi: 10.1038/nature11053
– volume: 13
  start-page: 131
  year: 2013
  ident: CR5
  article-title: Association of gut microbiota with post-operative clinical course in Crohn’s disease
  publication-title: BMC Gastroenterol.
  doi: 10.1186/1471-230X-13-131
– volume: 79
  start-page: 785
  year: 2000
  end-page: 792
  ident: CR38
  article-title: Campylobacter species in health, gingivitis, and periodontitis
  publication-title: J. Dent. Res.
  doi: 10.1177/00220345000790021301
– volume: 26
  start-page: 100
  year: 2019
  end-page: 113.e8
  ident: CR26
  article-title: Pathogenic autoreactive T and B cells cross-react with mimotopes expressed by a common human gut commensal to trigger autoimmunity
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2019.05.003
– volume: 10
  start-page: 1746
  year: 2019
  ident: CR12
  article-title: Gut microbiota analysis in postoperative lynch syndrome patients
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2019.01746
– volume: 292
  start-page: 344
  year: 1975
  end-page: 347
  ident: CR53
  article-title: Polymyositis and dermatomyositis: (First of Two Parts)
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM197502132920706
– volume: 10
  start-page: 2407
  year: 2019
  ident: CR65
  article-title: Rarefaction, alpha diversity, and statistics
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2019.02407
– volume: 63
  start-page: S118
  issue: Suppl 11
  year: 2011
  end-page: 157
  ident: CR55
  article-title: Measures of adult and juvenile dermatomyositis, polymyositis, and inclusion body myositis: Physician and Patient/Parent Global Activity, Manual Muscle Testing (MMT), Health Assessment Questionnaire (HAQ)/Childhood Health Assessment Questionnaire (C-HAQ), Childhood Myositis Assessment Scale (CMAS), Myositis Disease Activity Assessment Tool (MDAAT), Disease Activity Score (DAS), Short Form 36 (SF-36), Child Health Questionnaire (CHQ), physician global damage, Myositis Damage Index (MDI), Quantitative Muscle Testing (QMT), Myositis Functional Index-2 (FI-2), Myositis Activities Profile (MAP), Inclusion Body Myositis Functional Rating Scale (IBMFRS), Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), Cutaneous Assessment Tool (CAT), Dermatomyositis Skin Severity Index (DSSI), Skindex, and Dermatology Life Quality Index (DLQI)
  publication-title: Arthritis Care Res.
– volume: 37
  start-page: 852
  year: 2019
  end-page: 857
  ident: CR62
  article-title: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
  publication-title: Nat. Biotechnol.
  doi: 10.1038/s41587-019-0209-9
– volume: 13
  start-page: 5418
  year: 2022
  ident: CR14
  article-title: Batch effects removal for microbiome data via conditional quantile regression
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-022-33071-9
– volume: 371
  start-page: 2201
  year: 2008
  end-page: 2212
  ident: CR2
  article-title: Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood
  publication-title: Lancet Lond. Engl.
  doi: 10.1016/S0140-6736(08)60955-1
– volume: 8
  start-page: 43
  year: 2016
  ident: CR15
  article-title: An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis
  publication-title: Genome Med.
  doi: 10.1186/s13073-016-0299-7
– ident: CR67
– volume: 39
  start-page: 877
  year: 2013
  end-page: 904
  ident: CR3
  article-title: Developments in the classification and treatment of the juvenile idiopathic inflammatory myopathies
  publication-title: Rheum Dis. Clin. N. Am.
  doi: 10.1016/j.rdc.2013.06.001
– volume: 50
  start-page: 458
  year: 2020
  end-page: 462
  ident: CR56
  article-title: The validity and utility of the Cutaneous Disease Area and Severity Index (CDASI) as a clinical outcome instrument in dermatomyositis: A comprehensive review
  publication-title: Semin. Arthritis Rheum.
  doi: 10.1016/j.semarthrit.2020.01.002
– volume: 93
  year: 2023
  ident: CR30
  article-title: Infant gut microbiota and environment associate with juvenile idiopathic arthritis many years prior to disease onset, especially in genetically vulnerable children
  publication-title: EbioMedicine.
  doi: 10.1016/j.ebiom.2023.104654
– volume: 105
  start-page: 16731
  year: 2008
  end-page: 16736
  ident: CR16
  article-title: Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
  publication-title: Proc. Natl. Acad. Sci. U S A.
  doi: 10.1073/pnas.0804812105
– volume: 163
  start-page: 95
  year: 2015
  end-page: 107
  ident: CR57
  article-title: Regulators of gut motility revealed by a gnotobiotic model of diet-microbiome interactions related to travel
  publication-title: Cell.
  doi: 10.1016/j.cell.2015.08.059
– volume: 118
  year: 2021
  ident: CR32
  article-title: No evidence for colonization of oral bacteria in the distal gut in healthy adults
  publication-title: Proc. Natl. Acad. Sci.
  doi: 10.1073/pnas.2114152118
– volume: 7
  start-page: 2734
  year: 2019
  end-page: 2745
  ident: CR22
  article-title: Characterization of microbiota in systemic-onset juvenile idiopathic arthritis with different disease severities
  publication-title: World J. Clin. Cases.
  doi: 10.12998/wjcc.v7.i18.2734
– volume: 107
  start-page: 1913
  year: 2012
  end-page: 1922
  ident: CR19
  article-title: Microbiota of de-novo pediatric IBD: Increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn’s but not in ulcerative colitis
  publication-title: Am. J. Gastroenterol.
  doi: 10.1038/ajg.2012.335
– volume: 13
  year: 2022
  ident: CR27
  article-title: Characteristics of the gut microbiome and its relationship with peripheral CD4+ T Cell subpopulations and cytokines in rheumatoid arthritis
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2022.799602
– ident: CR11
– volume: 21
  start-page: 286
  year: 2020
  ident: CR23
  article-title: Gut microbiota in children with juvenile idiopathic arthritis: Characteristics, biomarker identification, and usefulness in clinical prediction
  publication-title: BMC Genomics.
  doi: 10.1186/s12864-020-6703-0
– volume: 92
  start-page: 25
  year: 2013
  end-page: 41
  ident: CR66
  article-title: The clinical phenotypes of the juvenile idiopathic inflammatory myopathies
  publication-title: Medicine (Baltimore).
  doi: 10.1097/MD.0b013e31827f264d
– volume: 46
  start-page: 3015
  year: 2002
  end-page: 3025
  ident: CR31
  article-title: Self epitopes shared between human skeletal myosin and Streptococcus pyogenes M5 protein are targets of immune responses in active juvenile dermatomyositis
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.10566
– volume: 16
  start-page: 31
  year: 2023
  ident: CR33
  article-title: Colonization resistance is dispensable for segregation of oral and gut microbiota
  publication-title: BMC Med. Genomics.
  doi: 10.1186/s12920-023-01449-3
– volume: 2
  start-page: e00458
  year: 2013
  ident: CR48
  article-title: Cohabiting family members share microbiota with one another and with their dogs
  publication-title: eLife.
  doi: 10.7554/eLife.00458
– volume: 1
  start-page: 1
  year: 2022
  ident: CR24
  article-title: Altered gut microbiome in patients with dermatomyositis
  publication-title: ACR Open Rheumatol.
– volume: 17
  start-page: 81
  year: 2019
  ident: CR41
  article-title: Oral health and plaque microbial profile in juvenile idiopathic arthritis
  publication-title: Pediatr. Rheumatol. Online J.
  doi: 10.1186/s12969-019-0387-5
– volume: 292
  start-page: 403
  year: 1975
  end-page: 407
  ident: CR54
  article-title: Polymyositis and dermatomyositis: (Second of Two Parts)
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM197502202920807
– volume: 29
  start-page: 765
  year: 2021
  end-page: 776.e3
  ident: CR13
  article-title: Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2021.02.021
– volume: 19
  start-page: E2938
  year: 2018
  ident: CR21
  article-title: Analysis of gut microbiota in rheumatoid arthritis patients: Disease-related dysbiosis and modifications induced by etanercept
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms19102938
– volume: 29
  start-page: 362
  year: 2021
  end-page: 377.e11
  ident: CR50
  article-title: Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2020.12.008
– volume: 50
  start-page: 3258
  year: 2012
  end-page: 3266
  ident: CR28
  article-title: Microbial dysbiosis in pediatric patients with Crohn’s disease
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/JCM.01396-12
– volume: 14
  year: 2019
  ident: CR44
  article-title: Dysbiotic salivary microbiota in dry mouth and primary Sjögren’s syndrome patients
  publication-title: PloS One.
  doi: 10.1371/journal.pone.0218319
– volume: 8
  start-page: e46923
  year: 2019
  ident: CR68
  article-title: Consistent and correctable bias in metagenomic sequencing experiments
  publication-title: eLife.
  doi: 10.7554/eLife.46923
– ident: CR10
– volume: 13
  start-page: 581
  year: 2016
  end-page: 583
  ident: CR61
  article-title: DADA2: High-resolution sample inference from Illumina amplicon data
  publication-title: Nat. Methods.
  doi: 10.1038/nmeth.3869
– volume: 21
  start-page: 2399
  year: 2017
  end-page: 2406
  ident: CR42
  article-title: Exploration of bacterial species associated with the salivary microbiome of individuals with a low susceptibility to dental caries
  publication-title: Clin. Oral Investig.
  doi: 10.1007/s00784-016-2035-5
– volume: 24
  start-page: 102508
  year: 2021
  ident: CR59
  article-title: Microbiome-encoded bile acid metabolism modulates colonic transit times
  publication-title: iScience.
  doi: 10.1016/j.isci.2021.102508
– volume: 40
  start-page: 1273
  year: 2001
  end-page: 1287
  ident: CR37
  article-title: alpha-Enolase of Streptococcus neumonia is a plasmin(ogen)-binding protein displayed on the bacterial cell surface
  publication-title: Mol. Microbiol.
  doi: 10.1046/j.1365-2958.2001.02448.x
– volume: 11
  start-page: 597966
  year: 2020
  ident: CR8
  article-title: Intestinal microbes in autoimmune and inflammatory disease
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.597966
– volume: 6
  start-page: 23561
  year: 2016
  ident: CR20
  article-title: Altered mucosal microbiome diversity and disease severity in Sjögren syndrome
  publication-title: Sci. Rep.
  doi: 10.1038/srep23561
– volume: 73
  start-page: 1986
  year: 2021
  end-page: 1993
  ident: CR45
  article-title: Differences in the oral microbiome in patients with early rheumatoid arthritis and individuals at risk of rheumatoid arthritis compared to healthy individuals
  publication-title: Arthritis Rheumatol Hoboken NJ.
  doi: 10.1002/art.41780
– volume: 40
  start-page: 394
  year: 2022
  end-page: 403
  ident: CR4
  article-title: Juvenile dermatomyositis. Where are we now?
  publication-title: Clin Exp Rheumatol.
  doi: 10.55563/clinexprheumatol/56ilob
– volume: 21
  start-page: 963
  year: 2015
  end-page: 972
  ident: CR51
  article-title: Using corticosteroids to reshape the gut microbiome: Implications for inflammatory bowel diseases
  publication-title: Inflamm. Bowel. Dis.
  doi: 10.1097/MIB.0000000000000332
– volume: 42
  start-page: 583
  year: 1998
  end-page: 589
  ident: CR46
  article-title: Incidence of Prevotella intermedia and Prevotella nigrescens in periodontal health and disease
  publication-title: Microbiol. Immunol.
  doi: 10.1111/j.1348-0421.1998.tb02328.x
– volume: 16
  start-page: e0248730
  year: 2021
  ident: CR58
  article-title: Variability in digestive and respiratory tract Ace2 expression is associated with the microbiome
  publication-title: PLOS ONE.
  doi: 10.1371/journal.pone.0248730
– volume: 562
  start-page: 589
  year: 2018
  end-page: 594
  ident: CR25
  article-title: The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
  publication-title: Nature.
  doi: 10.1038/s41586-018-0620-2
– volume: 10
  year: 2020
  ident: CR39
  article-title: Salivary oral microbiome of children with juvenile idiopathic arthritis: A norwegian cross-sectional study
  publication-title: Front. Cell Infect. Microbiol.
  doi: 10.3389/fcimb.2020.602239
– volume: 11
  start-page: 2639
  year: 2017
  end-page: 2643
  ident: CR60
  article-title: Exact sequence variants should replace operational taxonomic units in marker-gene data analysis
  publication-title: ISME J.
  doi: 10.1038/ismej.2017.119
– volume: 70
  start-page: 555
  year: 2018
  end-page: 565
  ident: CR49
  article-title: Effects of HLA-B27 on gut microbiota in experimental spondyloarthritis implicate an ecological model of dysbiosis
  publication-title: Arthritis Rheumatol.
  doi: 10.1002/art.40405
– volume: 9
  year: 2021
  ident: CR18
  article-title: Gut microbiota profile in pediatric patients with inflammatory bowel disease: A systematic review
  publication-title: Front. Pediatr.
  doi: 10.3389/fped.2021.626232
– volume: 49
  start-page: 300
  year: 2003
  end-page: 305
  ident: CR1
  article-title: US incidence of juvenile dermatomyositis, 1995–1998: Results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.11122
– volume: 22
  start-page: 66
  year: 2021
  ident: CR52
  article-title: Alteration of the gut microbiome in mycophenolate-induced enteropathy: Impacts on the profile of short-chain fatty acids in a mouse model
  publication-title: BMC Pharmacol. Toxicol.
  doi: 10.1186/s40360-021-00536-4
– volume: 8
  start-page: 17126
  year: 2018
  ident: CR34
  article-title: Variations in oral microbiome profiles in rheumatoid arthritis and osteoarthritis with potential biomarkers for arthritis screening
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-35473-6
– volume: 68
  start-page: 3140
  year: 2000
  end-page: 3146
  ident: CR35
  article-title: Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells
  publication-title: Infect. Immun.
  doi: 10.1128/IAI.68.6.3140-3146.2000
– volume: 10
  start-page: e1003531
  year: 2014
  ident: CR64
  article-title: Waste not, want not: Why rarefying microbiome data is inadmissible
  publication-title: PloS Comput Biol.
  doi: 10.1371/journal.pcbi.1003531
– volume: 49
  start-page: 1962
  year: 2010
  end-page: 1970
  ident: CR9
  article-title: Gingival capillary changes and oral motor weakness in juvenile dermatomyositis
  publication-title: Rheumatol. Oxf Engl.
  doi: 10.1093/rheumatology/keq189
– volume: 1
  start-page: 1
  year: 2018
  ident: CR7
  article-title: Gut microbiome structure and metabolic activity in inflammatory bowel disease
  publication-title: Nat. Microbiol.
– volume: 23
  start-page: 518
  year: 2014
  ident: 60225_CR6
  publication-title: Lupus.
  doi: 10.1177/0961203313501401
– volume: 68
  start-page: 3140
  year: 2000
  ident: 60225_CR35
  publication-title: Infect. Immun.
  doi: 10.1128/IAI.68.6.3140-3146.2000
– volume: 10
  start-page: 2407
  year: 2019
  ident: 60225_CR65
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2019.02407
– volume: 39
  start-page: 877
  year: 2013
  ident: 60225_CR3
  publication-title: Rheum Dis. Clin. N. Am.
  doi: 10.1016/j.rdc.2013.06.001
– volume: 13
  year: 2022
  ident: 60225_CR27
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2022.799602
– volume: 42
  start-page: 583
  year: 1998
  ident: 60225_CR46
  publication-title: Microbiol. Immunol.
  doi: 10.1111/j.1348-0421.1998.tb02328.x
– volume: 16
  start-page: e0248730
  year: 2021
  ident: 60225_CR58
  publication-title: PLOS ONE.
  doi: 10.1371/journal.pone.0248730
– volume: 10
  start-page: 1746
  year: 2019
  ident: 60225_CR12
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2019.01746
– volume: 21
  start-page: 286
  year: 2020
  ident: 60225_CR23
  publication-title: BMC Genomics.
  doi: 10.1186/s12864-020-6703-0
– volume: 13
  start-page: 5418
  year: 2022
  ident: 60225_CR14
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-022-33071-9
– volume: 70
  start-page: 555
  year: 2018
  ident: 60225_CR49
  publication-title: Arthritis Rheumatol.
  doi: 10.1002/art.40405
– volume: 19
  start-page: E2938
  year: 2018
  ident: 60225_CR21
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms19102938
– volume: 50
  start-page: 458
  year: 2020
  ident: 60225_CR56
  publication-title: Semin. Arthritis Rheum.
  doi: 10.1016/j.semarthrit.2020.01.002
– ident: 60225_CR11
  doi: 10.1038/s41598-018-22491-7
– volume: 49
  start-page: 300
  year: 2003
  ident: 60225_CR1
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.11122
– volume: 2
  start-page: e00458
  year: 2013
  ident: 60225_CR48
  publication-title: eLife.
  doi: 10.7554/eLife.00458
– ident: 60225_CR67
  doi: 10.1214/19-AOAS1283
– volume: 71
  start-page: 8228
  year: 2005
  ident: 60225_CR63
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.71.12.8228-8235.2005
– volume: 21
  start-page: 963
  year: 2015
  ident: 60225_CR51
  publication-title: Inflamm. Bowel. Dis.
  doi: 10.1097/MIB.0000000000000332
– volume: 10
  year: 2020
  ident: 60225_CR39
  publication-title: Front. Cell Infect. Microbiol.
  doi: 10.3389/fcimb.2020.602239
– volume: 11
  start-page: 597966
  year: 2020
  ident: 60225_CR8
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.597966
– volume: 292
  start-page: 403
  year: 1975
  ident: 60225_CR54
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM197502202920807
– volume: 11
  year: 2021
  ident: 60225_CR43
  publication-title: Front. Cell Infect. Microbiol.
  doi: 10.3389/fcimb.2021.629723
– volume: 13
  start-page: 131
  year: 2013
  ident: 60225_CR5
  publication-title: BMC Gastroenterol.
  doi: 10.1186/1471-230X-13-131
– volume: 29
  start-page: 362
  year: 2021
  ident: 60225_CR50
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2020.12.008
– volume: 13
  start-page: 581
  year: 2016
  ident: 60225_CR61
  publication-title: Nat. Methods.
  doi: 10.1038/nmeth.3869
– volume: 1
  start-page: 1
  year: 2022
  ident: 60225_CR24
  publication-title: ACR Open Rheumatol.
– volume: 49
  start-page: 1962
  year: 2010
  ident: 60225_CR9
  publication-title: Rheumatol. Oxf Engl.
  doi: 10.1093/rheumatology/keq189
– volume: 92
  start-page: 25
  year: 2013
  ident: 60225_CR66
  publication-title: Medicine (Baltimore).
  doi: 10.1097/MD.0b013e31827f264d
– volume: 50
  start-page: 3258
  year: 2012
  ident: 60225_CR28
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/JCM.01396-12
– volume: 10
  start-page: e1003531
  year: 2014
  ident: 60225_CR64
  publication-title: PloS Comput Biol.
  doi: 10.1371/journal.pcbi.1003531
– volume: 64
  start-page: 3083
  year: 2012
  ident: 60225_CR40
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.34539
– volume: 15
  start-page: 1183
  year: 2009
  ident: 60225_CR17
  publication-title: Inflamm. Bowel Dis.
  doi: 10.1002/ibd.20903
– volume: 58
  start-page: 28
  year: 2018
  ident: 60225_CR36
  publication-title: Adv. Rheumatol.
  doi: 10.1186/s42358-018-0024-x
– volume: 562
  start-page: 589
  year: 2018
  ident: 60225_CR25
  publication-title: Nature.
  doi: 10.1038/s41586-018-0620-2
– volume: 371
  start-page: 2201
  year: 2008
  ident: 60225_CR2
  publication-title: Lancet Lond. Engl.
  doi: 10.1016/S0140-6736(08)60955-1
– volume: 6
  start-page: 23561
  year: 2016
  ident: 60225_CR20
  publication-title: Sci. Rep.
  doi: 10.1038/srep23561
– volume: 63
  start-page: S118
  issue: Suppl 11
  year: 2011
  ident: 60225_CR55
  publication-title: Arthritis Care Res.
– volume: 292
  start-page: 344
  year: 1975
  ident: 60225_CR53
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM197502132920706
– volume: 22
  start-page: 66
  year: 2021
  ident: 60225_CR52
  publication-title: BMC Pharmacol. Toxicol.
  doi: 10.1186/s40360-021-00536-4
– volume: 8
  start-page: 43
  year: 2016
  ident: 60225_CR15
  publication-title: Genome Med.
  doi: 10.1186/s13073-016-0299-7
– volume: 7
  start-page: 2734
  year: 2019
  ident: 60225_CR22
  publication-title: World J. Clin. Cases.
  doi: 10.12998/wjcc.v7.i18.2734
– volume: 40
  start-page: 1273
  year: 2001
  ident: 60225_CR37
  publication-title: Mol. Microbiol.
  doi: 10.1046/j.1365-2958.2001.02448.x
– volume: 11
  start-page: 2639
  year: 2017
  ident: 60225_CR60
  publication-title: ISME J.
  doi: 10.1038/ismej.2017.119
– volume: 93
  year: 2023
  ident: 60225_CR30
  publication-title: EbioMedicine.
  doi: 10.1016/j.ebiom.2023.104654
– volume: 107
  start-page: 1913
  year: 2012
  ident: 60225_CR19
  publication-title: Am. J. Gastroenterol.
  doi: 10.1038/ajg.2012.335
– volume: 46
  start-page: 3015
  year: 2002
  ident: 60225_CR31
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.10566
– volume: 9
  year: 2021
  ident: 60225_CR18
  publication-title: Front. Pediatr.
  doi: 10.3389/fped.2021.626232
– volume: 160
  start-page: 1118
  year: 2021
  ident: 60225_CR29
  publication-title: Gastroenterology.
  doi: 10.1053/j.gastro.2020.11.050
– volume: 118
  year: 2021
  ident: 60225_CR32
  publication-title: Proc. Natl. Acad. Sci.
  doi: 10.1073/pnas.2114152118
– volume: 37
  start-page: 852
  year: 2019
  ident: 60225_CR62
  publication-title: Nat. Biotechnol.
  doi: 10.1038/s41587-019-0209-9
– volume: 29
  start-page: 765
  year: 2021
  ident: 60225_CR13
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2021.02.021
– volume: 8
  start-page: 17126
  year: 2018
  ident: 60225_CR34
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-35473-6
– ident: 60225_CR10
  doi: 10.1128/mSystems.00117-19
– volume: 105
  start-page: 16731
  year: 2008
  ident: 60225_CR16
  publication-title: Proc. Natl. Acad. Sci. U S A.
  doi: 10.1073/pnas.0804812105
– volume: 26
  start-page: 100
  year: 2019
  ident: 60225_CR26
  publication-title: Cell Host Microbe.
  doi: 10.1016/j.chom.2019.05.003
– volume: 21
  start-page: 2399
  year: 2017
  ident: 60225_CR42
  publication-title: Clin. Oral Investig.
  doi: 10.1007/s00784-016-2035-5
– volume: 79
  start-page: 785
  year: 2000
  ident: 60225_CR38
  publication-title: J. Dent. Res.
  doi: 10.1177/00220345000790021301
– volume: 24
  start-page: 102508
  year: 2021
  ident: 60225_CR59
  publication-title: iScience.
  doi: 10.1016/j.isci.2021.102508
– volume: 17
  start-page: 81
  year: 2019
  ident: 60225_CR41
  publication-title: Pediatr. Rheumatol. Online J.
  doi: 10.1186/s12969-019-0387-5
– volume: 73
  start-page: 1986
  year: 2021
  ident: 60225_CR45
  publication-title: Arthritis Rheumatol Hoboken NJ.
  doi: 10.1002/art.41780
– volume: 486
  start-page: 222
  year: 2012
  ident: 60225_CR47
  publication-title: Nature.
  doi: 10.1038/nature11053
– volume: 163
  start-page: 95
  year: 2015
  ident: 60225_CR57
  publication-title: Cell.
  doi: 10.1016/j.cell.2015.08.059
– volume: 40
  start-page: 394
  year: 2022
  ident: 60225_CR4
  publication-title: Clin Exp Rheumatol.
  doi: 10.55563/clinexprheumatol/56ilob
– volume: 1
  start-page: 1
  year: 2018
  ident: 60225_CR7
  publication-title: Nat. Microbiol.
– volume: 16
  start-page: 31
  year: 2023
  ident: 60225_CR33
  publication-title: BMC Med. Genomics.
  doi: 10.1186/s12920-023-01449-3
– volume: 14
  year: 2019
  ident: 60225_CR44
  publication-title: PloS One.
  doi: 10.1371/journal.pone.0218319
– volume: 8
  start-page: e46923
  year: 2019
  ident: 60225_CR68
  publication-title: eLife.
  doi: 10.7554/eLife.46923
SSID ssj0000529419
Score 2.4290211
Snippet Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective,...
Abstract Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center,...
SourceID doaj
proquest
pubmed
crossref
springer
SourceType Open Website
Aggregation Database
Index Database
Publisher
StartPage 16158
SubjectTerms 631/326/2565/2134
692/4023/1670/427
Adolescent
Adult
Child
Child, Preschool
Children
Community structure
Dermatomyositis
Dermatomyositis - genetics
Dermatomyositis - microbiology
Dysbiosis - microbiology
Families & family life
Feces
Feces - microbiology
Female
Gastrointestinal Microbiome - genetics
Humanities and Social Sciences
Humans
Immunomodulation
Intestinal microflora
Male
Microbiomes
Microbiota - genetics
Mouth - microbiology
multidisciplinary
Observational studies
Oral cavity
Prospective Studies
RNA, Ribosomal, 16S - genetics
rRNA 16S
Saliva
Saliva - microbiology
Science
Science (multidisciplinary)
Siblings
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1BSxwxFA6yUPAi2mqdupYUvGlwMskkmaOWLkuhPbnoLUwmCay4M9LZPey_9yWZXRUrvfQ6yYTkveR975G87yF0FpIZVVUbkou6JFwYSwyjlAgFhgE8WCYjT8Gv32I64z_vyrsXpb7Cm7BED5wEd1mw0jeUmhxwkzvpDLgItuRSMiZVGZOnC8C8F8FUYvUuKk6rIUsmZ-qyB6QK2WQFJwJwqyT5KySKhP1_8zLf3JBG4Jnso73BY8RXaaYHaMe1H9GHVENy_QndxtIVsItw87AKrAcwCO48tuvezDv4B4ccfFy3FnsHCsGLeeJeWrgez1t8vwJzB6YB22Cjl91iHZ9x9YdoNvlx831KhmoJpOFMLImyNIS6lbfSNVRIUxnLXcM8ayDGcLUxNUB1IKgTngqveGOUtCBcx6FP7tkRGrVd644RFlzy2nHpnKjAoQOnkjtrIPZh1Bswjhk630hOPyZSDB0vs5nSSc4a5KyjnHWeoesg3G3PQGgdP4Ca9aBm_S81Z2i8UY0eTlmvwT5VIoJwhr5tm-F8hEuPunXdKvVR4OTRKkOfk0q3MwncghBcQMvFRsfPg7-_oC__Y0EnaLcImzFwdBZjNFr-WblT8G-W5mvcyk_OJfFL
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Scholars Portal Journals: Open Access
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fi9QwEB6OE8EX0fNX9e6I4JtGN02apA9yqHgcwvnk4r2Fpklkj9tWt7vg_vdOknZFXH1tkpLOTGa-IZ1vAF7EYkZdN5bOZFNRIa2jljNGpUbHgAiWq8RTcPlZXszFp6vq6gCmdkejAIe9qV3sJzVf3bz--WN7hgf-bS4Z128GDEKxUKwUVGJIqiim8LcwMqnY0eByhPuZ67usBavH2pn9S_-IT4nGfx_2_OveNIWj83twd8SR5F1W_H048N0R3M6dJbcP4GtqaIG2RdqbTeRCwJeQPhC3HeyixzUkVuaTpnMkeFQTWS4yI9PSD2TRkesNOkF0GMRFz73ul9v0c9fwEObnH798uKBjDwXaCi7XVDsWE-A6OOVbJpWtrRO-5YG3mHn4xtoGA3ikrZOByaBFa7VyVWi9wDmzwB_BYdd3_gkQKZRovFDeyxphHkJN4Z3FjIizYNFlFvBykpz5nqkyTLri5tpkORuUs0lyNrMC3kfh7mZGmuv0oF99M-OpMSXHnTBmZwiahFfeIj50lVCKc6UR6xVwPKnGTKZj0GvVMoXmAp7vhvHUxKuQpvP9Js_RCP1YXcDjrNLdTiLjIKYcOPJq0vHvl__7g57-fy_P4E4ZzSxycpbHcLhebfwJ4pm1PU1G-gu2V-2j
  priority: 102
  providerName: Scholars Portal
– databaseName: HAS SpringerNature Open Access 2022
  dbid: AAJSJ
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3BTtwwEB0hUCUuVaEtTaHIlbi1FnHs2M5xWxWhleilRXCz4tiutuomFdk97N937CSLEPTANbYjZ8aeeZPxPAOcxWJGXdWW5rIuqZDWUcsZo1KjYUAEy1XiKbj6Li-vxfy2vN2BYqqFSYf2E6VlMtPT6bDzHh1NLAYrBJXodkqKYfpepGrHtb03m81_zLd_VmLuSrBqrJDJuX5i8AMvlMj6n0KYj7KjyelcvIKXI1oks2F-B7Dj20N4MdwfuXkNN-naClxBpPmzjowH-BLSBeI2vV10OIbE-ntSt44Ej8ogy8XAu7T0PVm05PcaTR2aBeKifV51y006wtW_geuLbz-_XtLxpgTaCC5XVDsWw9wqOOUbJpWtrBO-4YE3GF_42toa3XQkp5OByaBFY7VyZWi8wD554G9ht-1a_w6IFErUXijvZYVgDgGl8M5i3MNZsGgYM_g0Sc78HQgxTEpkc20GORuUs0lyNnkGX6Jwtz0jmXV60N39MqNyTcFxJozZHKGR8MpbRIGuFEpxrjQiugxOJtWYcYf1Bm1TJZMDzuDjthn3Rkx41K3v1kMfjQCPVRkcDSrdziTyCmJggS2fJx3fv_z_H_T-ed2PYb-Iyy4ycRYnsLu6W_sPiGJW9nRctv8ALKfpnA
  priority: 102
  providerName: Springer Nature
Title Familial clustering of dysbiotic oral and fecal microbiomes in juvenile dermatomyositis
URI https://link.springer.com/article/10.1038/s41598-024-60225-0
https://www.ncbi.nlm.nih.gov/pubmed/38997299
https://www.proquest.com/docview/3079613036
https://www.proquest.com/docview/3079856219
https://doaj.org/article/235fc11b09764e7eb851d54773378551
Volume 14
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fa9swEBZby2Avo_vttQsa7G0TtSJZkp9GGlpKoGVsK8ubsCxpZCx2VycP-e93JzspY-1ebLBlI9-d7j7prO8IeY-bGU1ZOZarqmBSOc-c4JwpA44BEKzQiafg4lKdX8nZvJgPC27d8Fvl1icmR-3bGtfIj8EWS5Uc7qfr3wyrRmF2dSih8ZDsI3UZWrWe690aC2axJC-HvTK5MMcdxCvcUzaWTEH0Klj-VzxKtP13Yc1_8qQp_JwdkCcDbqSTXtFPyYPQPCOP-kqSm-fkeypgAbZE619r5D6Al9A2Ur_p3KKFZyjuxKdV42kMoBa6XPQMTMvQ0UVDf67B6YGDoB499apdbtLPXN0LcnV2-m16zoaaCayWQq2Y8RwnvGX0OtRcaVc6L0MtoqhhphEq5yoI2EhTpyJX0cjaGe2LWAcJbfIoXpK9pm3Ca0KV1LIKUoegSoB1AC1l8A5mQIJHBy4yIx-2krPXPTWGTSltYWwvZwtytknONs_ICQp31xJprdOF9uaHHUaJHQvoCecuB5Akgw4O8KAvpNZCaAPYLiNHW9XYYax19tYyMvJudxtGCaY-qia0676NAajHy4y86lW66wkyDMIUA-583Or49uX3f9Cb__flkDweo5khB-f4iOytbtbhLeCXlRslIx2R_clk9nUG55PTy89f4OpUTUdpTQCOF9L8AST38Es
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIgQXxJtAASPBCazGsWMnB4R4VVv6OLVibyaObbRVNynNrtD-KX4jYyfZCvG49Zo4ljMznvnG45kBeBGSGYuyMjSVVU6FNJYazhiVBSoGRLBcxToFB4dyciw-T_PpBvwcc2HCtcpRJ0ZFbds6nJFvoyyWMirct2ffaegaFaKrYwuNXiz23OoHumzdm92PyN-XWbbz6ejDhA5dBWgtuFzQwrLgEpbeKlczqUxprHA197xGLO4qYyo0aaGQm_RM-kLUplA297UTOCb1HOe9AlfR8KbB2VNTtT7TCVEzwcohNyflxXaH9jHksGWCSrSWOU1_s3-xTcDfsO0fcdlo7nZuwc0Bp5J3vWDdhg3X3IFrfefK1V34EhtmoOyS-nQZai3gJKT1xK46M2vxGxIy_0nVWOIdigGZz_qKT3PXkVlDTpaoZFEhERssw6Kdr-Llse4eHF8KNe_DZtM27iEQKZSonFDOyRJhJEJZ4axBj4szb1AlJ_BqpJw-60tx6BhC54Xu6ayRzjrSWacJvA_EXY8MZbTjg_b8mx52pc44roQxkyIoE045g_jT5kIpzlWBWDKBrZE1etjbnb6QxASer1_jrgyhlqpx7bIfUyC0ZGUCD3qWrlcSKhqiS4NvXo88vpj83z_06P9reQbXJ0cH-3p_93DvMdzIgsiF-p_ZFmwuzpfuCWKnhXkaBZbA18veIb8AGRgoZw
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VrUBcEG8CBYwEJ7A2iR07OSBEaVcthVWFqOjNxLFdbcUmpdkV2r_Gr2PsJFshHrdeN47lHc_jm4z9DcBzf5kxL0pNY1FmlAttqGZJQkWOjgERLJOBp-DjVOwd8ffH2fEG_BzuwvhjlYNPDI7aNJX_Rj5GXSxEcLhj1x-LONyZvDn7Tn0HKV9pHdppdCpyYFc_MH1rX-_v4F6_SNPJ7ud3e7TvMEArzsSC5ibx6WHhjLRVIqQutOG2Yo5ViMttqXWJ4c2TugmXCJfzSufSZK6yHMfEjuG8V2BT-qxoBJvbu9PDT-svPL6GxpOiv6kTs3zcYrT0N9pSTgXGzozGv0XD0DTgb0j3jyptCH6Tm3CjR63kbadmt2DD1rfhatfHcnUHvoT2GajJpPq29MwLOAlpHDGrVs8afId4HgBS1oY4i0pB5rOO_2luWzKryekSXS66J2J8nFg081U4StbehaNLkec9GNVNbR8AEVzy0nJprSgQVCKw5dZozL9Y4jQ66AheDpJTZx0xhwoFdZarTs4K5ayCnFUcwbYX7nqkJ9UOPzTnJ6q3UZUyXEmS6BghGrfSakSjJuNSMiZzRJYRbA1bo3pLb9WFXkbwbP0YbdQXXsraNstuTI5AMykiuN9t6Xolnt8QExx88mrY44vJ__2HHv5_LU_hGlqH-rA_PXgE11OvcZ4MNN2C0eJ8aR8jkFroJ73GEvh62UbyCwvaLgI
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Familial+clustering+of+dysbiotic+oral+and+fecal+microbiomes+in+juvenile+dermatomyositis&rft.jtitle=Scientific+reports&rft.au=Koester%2C+Sean+T&rft.au=Chow%2C+Albert&rft.au=Pepper-Tunick%2C+Evan&rft.au=Lee%2C+Peggy&rft.date=2024-07-12&rft.pub=Nature+Publishing+Group&rft.eissn=2045-2322&rft.volume=14&rft.issue=1&rft.spage=16158&rft_id=info:doi/10.1038%2Fs41598-024-60225-0&rft.externalDBID=HAS_PDF_LINK
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2045-2322&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2045-2322&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2045-2322&client=summon