Dual mechanisms for the regulation of brain-derived neurotrophic factor by valproic acid in neural progenitor cells

• Published in: The Korean journal of physiology & pharmacology Vol. 22; no. 6; pp. 679 - 688
• Main Authors: Ko, Hyun Myung, Jin, Yeonsun, Park, Hyun Ho, Lee, Jong Hyuk, Jung, Seung Hyo, Choi, So Young, Lee, Sung Hoon, Shin, Chan Young
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Physiological Society and The Korean Society of Pharmacology 01.11.2018; 대한약리학회
• Subjects: Original; 약리학; Methyl-CpG-binding protein 2; Brain-derived neurotrophic factor; Valproic acid; Tissue plasminogen activator

Autism spectrum disorders (ASDs) are neurodevelopmental disorders that share behavioral features, the results of numerous studies have suggested that the underlying causes of ASDs are multifactorial. Behavioral and/or neurobiological analyses of ASDs have been performed extensively using a valid mod...