Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns

• Published in: The world journal of biological psychiatry Vol. 10; no. 4_3; pp. 856 - 869
• Main Authors: Mazor, Adi, Matar, Michael A., Kaplan, Zeev, Kozlovsky, Nitsan, Zohar, Joseph, Cohen, Hagit
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 2009; Taylor & Francis
• Subjects: animal model; Animals; Anxiety Disorders - epidemiology; Anxiety Disorders - etiology; Behavior, Animal; Corticosterone - blood; Depressive Disorder, Major - epidemiology; Depressive Disorder, Major - etiology; Disease Models, Animal; Estrous Cycle; extreme behavioural response; Female; gender; Incidence; Male; Maze Learning; Posttraumatic stress disorder; Prevalence; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sex Factors; Social Behavior; Stress Disorders, Post-Traumatic - psychology

Background. Most epidemiological studies report higher prevalence rates of stress-related disorders such as acute stress disorder, post-traumatic stress disorder (PTSD) and major depressive disorder in women than in men. Few animal models of PTSD have taken gender differences into account and have t...