Mixed effect regression analysis for a cluster-based two-stage outcome-auxiliary-dependent sampling design with a continuous outcome

• Published in: Biostatistics (Oxford, England) Vol. 13; no. 4; pp. 650 - 664
• Main Authors: Xu, W., Zhou, H.
• Format: Journal Article
• Language: English
• Published: England Oxford Publishing Limited (England) 01.09.2012; Oxford University Press
• Subjects: Biomedical research; Child; Cluster Analysis; Computer Simulation; Cost reduction; Environmental Pollutants - poisoning; Female; Humans; Intelligence; Likelihood Functions; Male; Maternal Exposure - adverse effects; Models, Statistical; Mothers; Parameter estimation; Polychlorinated Biphenyls - poisoning; Pregnancy; Regression analysis; Research Design; Simulation

Two-stage design is a well-known cost-effective way for conducting biomedical studies when the exposure variable is expensive or difficult to measure. Recent research development further allowed one or both stages of the two-stage design to be outcome dependent on a continuous outcome variable. This...