Concurrent treatment with ursolic acid and low-intensity treadmill exercise improves muscle atrophy and related outcomes in rats
The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle at...
Saved in:
| Published in | The Korean journal of physiology & pharmacology Vol. 22; no. 4; pp. 427 - 436 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
The Korean Physiological Society and The Korean Society of Pharmacology
01.07.2018
대한약리학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1226-4512 2093-3827 |
| DOI | 10.4196/kjpp.2018.22.4.427 |
Cover
| Abstract | The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of
and
, but did not have significant change in hypertrophy-related gene expression of Akt and
. The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions. |
|---|---|
| AbstractList | The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of MuRF1 and atrogin-1, but did not have significant change in hypertrophy-related gene expression of Akt and mTOR. The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions.The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of MuRF1 and atrogin-1, but did not have significant change in hypertrophy-related gene expression of Akt and mTOR. The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions. The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10–12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10–12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of MuRF1 and atrogin-1 , but did not have significant change in hypertrophy-related gene expression of Akt and mTOR . The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions. The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy–related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy–induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of MuRF1 and atrogin-1 , but did not have significant change in hypertrophy-related gene expression of Akt and mTOR. The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions. KCI Citation Count: 4 The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, 0° grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, 0° grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of and , but did not have significant change in hypertrophy-related gene expression of Akt and . The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions. |
| Author | Kim, Sang Hyun Noh, Eun Bi Park, Gi Duck Kang, Yun Seok Seo, Dae Yun Kim, Jae Cheol Seo, Baek Woon |
| AuthorAffiliation | 2 Department of Physiology, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea 3 Department of Leisure Sport, Kyungpook National University, Sangju 37224, Korea 1 Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea |
| AuthorAffiliation_xml | – name: 2 Department of Physiology, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea – name: 1 Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea – name: 3 Department of Leisure Sport, Kyungpook National University, Sangju 37224, Korea |
| Author_xml | – sequence: 1 givenname: Jae Cheol surname: Kim fullname: Kim, Jae Cheol organization: Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea – sequence: 2 givenname: Yun Seok surname: Kang fullname: Kang, Yun Seok organization: Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea – sequence: 3 givenname: Eun Bi surname: Noh fullname: Noh, Eun Bi organization: Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea – sequence: 4 givenname: Baek Woon surname: Seo fullname: Seo, Baek Woon organization: Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea – sequence: 5 givenname: Dae Yun surname: Seo fullname: Seo, Dae Yun organization: Department of Physiology, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea – sequence: 6 givenname: Gi Duck surname: Park fullname: Park, Gi Duck organization: Department of Leisure Sport, Kyungpook National University, Sangju 37224, Korea – sequence: 7 givenname: Sang Hyun surname: Kim fullname: Kim, Sang Hyun organization: Department of Sports Science, College of Natural Science, Chonbuk National University, Jeonju 54896, Korea |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29962857$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002369294$$DAccess content in National Research Foundation of Korea (NRF) |
| BookMark | eNp9kktv1DAUhS1UREvpH2CBvIRFBtuJH9kgVSMelSohobK2PM4NY8axg-20nR0_nWSmRcCC1bV0v3OOdH2eo5MQAyD0kpJVQ1vxdvd9HFeMULVibNWsGiafoDNG2rqqFZMn6IwyJqqGU3aKLnJ2G0IUJ1yR9hk6ZW0rmOLyDP1cx2CnlCAUXBKYMiyvO1e2eEo5emexsa7DJnTYx7vKhQIhu7I_0N3gvMdwD8m6DNgNY4q3kPEwZesBm5LiuN0fxAm8KdDhOBUbh5lxASdT8gv0tDc-w8XDPEdfP7y_WX-qrj9_vFpfXle2qUWpmOo31ioO0HEhudhI6EE1QFVtpWiUXfadkRy6mjAlBbC-5UT0kgm-EaQ-R2-OviH1emedjsYd5reod0lffrm50rWgvBHNzL47suO0GaCz80mS8XpMbjBpf1D-vQluO_vcakFoq-Ri8PrBIMUfE-SiB5cteG8CxClrRkQtKSGCzuirP7N-hzx-0QyoI2BTzDlBr60rpri4RDuvKdFLIfRSCL0UQjOmGz0XYpayf6SP7v8R_QJ5mL5T |
| CitedBy_id | crossref_primary_10_20463_jenb_2019_0022 crossref_primary_10_1002_jcsm_13706 crossref_primary_10_1002_iub_2435 crossref_primary_10_3390_brainsci10120933 crossref_primary_10_4163_jnh_2024_57_1_27 crossref_primary_10_1016_j_taap_2020_115271 crossref_primary_10_1039_C9FO00912D crossref_primary_10_4196_kjpp_2024_28_6_515 crossref_primary_10_1007_s10974_021_09610_0 crossref_primary_10_3390_ijms23126825 crossref_primary_10_3390_nu17060969 crossref_primary_10_3390_nu15184083 crossref_primary_10_1007_s12565_023_00741_7 crossref_primary_10_3389_fpubh_2024_1302175 crossref_primary_10_1152_japplphysiol_01077_2018 crossref_primary_10_1152_japplphysiol_00752_2019 crossref_primary_10_3390_nu13061914 crossref_primary_10_3390_antiox9060529 crossref_primary_10_1590_1517_8692202329012021_0396 crossref_primary_10_1038_s41598_020_61599_7 crossref_primary_10_1371_journal_pone_0215335 crossref_primary_10_14336_AD_2023_0713 crossref_primary_10_1016_j_ejphar_2024_176429 crossref_primary_10_1111_jfbc_14202 crossref_primary_10_1016_j_jnutbio_2021_108619 crossref_primary_10_4162_nrp_2022_16_2_147 |
| Cites_doi | 10.1002/mus.24316 10.1016/j.cmet.2004.12.003 10.1016/j.mehy.2015.02.014 10.3177/jnsv.63.277 10.1016/S0140-6736(11)60749-6 10.1080/07315724.2015.1132019 10.1016/S0092-8674(01)00240-9 10.1002/mnfr.201400670 10.1016/j.cmet.2011.03.020 10.1016/j.nutres.2017.01.001 10.1016/0304-3835(95)03856-R 10.1016/j.phrs.2015.11.009 10.1016/j.atherosclerosis.2011.06.013 10.1152/jappl.2001.91.3.1017 10.1111/j.1750-3841.2008.00864.x 10.1016/j.bbrc.2004.05.183 10.1038/srep31142 10.7150/ijbs.4262 10.1016/j.cell.2008.06.051 10.1159/000365947 10.1152/ajpendo.90532.2008 10.1371/journal.pone.0039332 10.1101/cshperspect.a029751 10.1007/s13139-011-0087-7 10.1038/415339a 10.1001/jama.1990.03440220053029 10.1371/journal.pone.0110020 10.1056/NEJMcibr0806723 10.1111/j.1447-0594.2012.00923.x 10.1155/2016/4301621 10.1152/jappl.1988.64.3.1038 10.1155/2013/218970 10.1124/jpet.112.191759 10.1152/japplphysiol.91566.2008 10.1089/jmf.2010.0267 10.1093/ageing/afy009 10.4196/kjpp.2014.18.5.441 10.1042/cs0990309 10.1089/jmf.2014.3401 10.1016/j.cmet.2016.10.022 10.1080/13697137.2017.1286890 10.1152/japplphysiol.00031.2011 10.1152/japplphysiol.01161.2012 10.1139/h05-028 10.1007/s00198-015-3241-8 10.1111/cpf.12117 10.1002/mnfr.200700389 10.1161/CIRCULATIONAHA.111.047381 10.1002/cpt.533 10.3389/fphys.2015.00296 10.1152/ajpendo.00302.2013 10.1074/jbc.M115.681445 10.1093/ageing/24.4.292 10.1161/CIRCRESAHA.109.205310 10.1093/gerona/glx023 10.1039/C7FO00127D 10.1242/jeb.017640 10.1161/01.CIR.87.2.470 10.1590/S0100-879X2002001100010 10.1152/jappl.1997.83.6.1947 |
| ContentType | Journal Article |
| Copyright | Copyright © Korean J Physiol Pharmacol 2018 The Korean Physiological Society and The Korean Society of Pharmacology |
| Copyright_xml | – notice: Copyright © Korean J Physiol Pharmacol 2018 The Korean Physiological Society and The Korean Society of Pharmacology |
| DBID | AAYXX CITATION NPM 7X8 5PM ACYCR |
| DOI | 10.4196/kjpp.2018.22.4.427 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic PubMed Central (Full Participant titles) Korean Citation Index |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic PubMed |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology |
| EISSN | 2093-3827 |
| EndPage | 436 |
| ExternalDocumentID | oai_kci_go_kr_ARTI_3615464 PMC6019874 29962857 10_4196_kjpp_2018_22_4_427 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: ; grantid: NRF-2016S1A5A8019355 – fundername: ; |
| GroupedDBID | --- 5-W 53G 5GY 8JR 8XY 9ZL AAYXX ABDBF ACUHS ADBBV AENEX ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL CITATION DIK E3Z EBD EF. ESX F5P GX1 HYE KVFHK MK0 OK1 P2P P5Y P6G RPM TR2 TUS NPM 7X8 5PM .UV ABPTK ACYCR |
| ID | FETCH-LOGICAL-c436t-28fbcc85eed56756b7efe84e183c7648c8fbcda75ed302876e2f9506f7265b603 |
| ISSN | 1226-4512 |
| IngestDate | Tue Nov 21 21:41:33 EST 2023 Thu Aug 21 18:24:17 EDT 2025 Fri Jul 11 06:08:48 EDT 2025 Wed Mar 05 08:56:26 EST 2025 Tue Jul 01 02:33:16 EDT 2025 Thu Apr 24 23:03:10 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Keywords | Aging Muscle atrophy Ursolic acid Exercise |
| Language | English |
| License | http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c436t-28fbcc85eed56756b7efe84e183c7648c8fbcda75ed302876e2f9506f7265b603 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC6019874 |
| PMID | 29962857 |
| PQID | 2063710061 |
| PQPubID | 23479 |
| PageCount | 10 |
| ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_3615464 pubmedcentral_primary_oai_pubmedcentral_nih_gov_6019874 proquest_miscellaneous_2063710061 pubmed_primary_29962857 crossref_citationtrail_10_4196_kjpp_2018_22_4_427 crossref_primary_10_4196_kjpp_2018_22_4_427 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2018-07-01 |
| PublicationDateYYYYMMDD | 2018-07-01 |
| PublicationDate_xml | – month: 07 year: 2018 text: 2018-07-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Korea (South) |
| PublicationPlace_xml | – name: Korea (South) |
| PublicationTitle | The Korean journal of physiology & pharmacology |
| PublicationTitleAlternate | Korean J Physiol Pharmacol |
| PublicationYear | 2018 |
| Publisher | The Korean Physiological Society and The Korean Society of Pharmacology 대한약리학회 |
| Publisher_xml | – name: The Korean Physiological Society and The Korean Society of Pharmacology – name: 대한약리학회 |
| References | Feng (10.4196/kjpp.2018.22.4.427_ref3) 2011; 111 Church (10.4196/kjpp.2018.22.4.427_ref66) 2016; 35 Cho (10.4196/kjpp.2018.22.4.427_ref67) 2016; 2016 Rao (10.4196/kjpp.2018.22.4.427_ref51) 2011; 14 Shishodia (10.4196/kjpp.2018.22.4.427_ref21) 2003; 63 Daly (10.4196/kjpp.2018.22.4.427_ref15) 2017; 20 Watanabe (10.4196/kjpp.2018.22.4.427_ref12) 2014; 34 Souza (10.4196/kjpp.2018.22.4.427_ref61) 2014; 9 Winder (10.4196/kjpp.2018.22.4.427_ref53) 2001; 91 Handschin (10.4196/kjpp.2018.22.4.427_ref45) 2016; 103 Kondo (10.4196/kjpp.2018.22.4.427_ref38) 2015; 51 Craig (10.4196/kjpp.2018.22.4.427_ref46) 2015; 6 Furlanetto (10.4196/kjpp.2018.22.4.427_ref58) 2016; 15 Chen (10.4196/kjpp.2018.22.4.427_ref68) 2017; 8 Eng (10.4196/kjpp.2018.22.4.427_ref64) 2008; 211 Ikeda (10.4196/kjpp.2018.22.4.427_ref30) 2008; 52 Cárdenas (10.4196/kjpp.2018.22.4.427_ref31) 2004; 320 Ji (10.4196/kjpp.2018.22.4.427_ref62) 2015; 61 Fiatarone (10.4196/kjpp.2018.22.4.427_ref14) 1990; 263 He (10.4196/kjpp.2018.22.4.427_ref6) 2016; 27 Frontera (10.4196/kjpp.2018.22.4.427_ref13) 1988; 64 Ogasawara (10.4196/kjpp.2018.22.4.427_ref65) 2013; 305 Lexell (10.4196/kjpp.2018.22.4.427_ref63) 1995; 50 Lavender (10.4196/kjpp.2018.22.4.427_ref20) 2006; 31 Wen (10.4196/kjpp.2018.22.4.427_ref18) 2011; 378 Bedford (10.4196/kjpp.2018.22.4.427_ref39) 1979; 47 Jeong (10.4196/kjpp.2018.22.4.427_ref26) 2015; 18 Naseeb (10.4196/kjpp.2018.22.4.427_ref49) 2017; 40 Narkar (10.4196/kjpp.2018.22.4.427_ref44) 2008; 134 Kahn (10.4196/kjpp.2018.22.4.427_ref54) 2005; 1 Tanaka (10.4196/kjpp.2018.22.4.427_ref2) 1997; 83 Vazeille (10.4196/kjpp.2018.22.4.427_ref34) 2008; 295 Wilson (10.4196/kjpp.2018.22.4.427_ref4) 1993; 87 Achiwa (10.4196/kjpp.2018.22.4.427_ref28) 2005; 13 Madaro (10.4196/kjpp.2018.22.4.427_ref35) 2008; 18 Ebert (10.4196/kjpp.2018.22.4.427_ref1) 2015; 290 Kim (10.4196/kjpp.2018.22.4.427_ref7) 2013; 13 Goodyear (10.4196/kjpp.2018.22.4.427_ref17) 2008; 359 Ogasawara (10.4196/kjpp.2018.22.4.427_ref56) 2013; 114 Sohn (10.4196/kjpp.2018.22.4.427_ref32) 1995; 94 Copp (10.4196/kjpp.2018.22.4.427_ref41) 2009; 106 Elkin (10.4196/kjpp.2018.22.4.427_ref5) 2000; 99 Kim (10.4196/kjpp.2018.22.4.427_ref40) 2017; 63 Gielen (10.4196/kjpp.2018.22.4.427_ref9) 2012; 125 Minokoshi (10.4196/kjpp.2018.22.4.427_ref55) 2002; 415 Gorianovas (10.4196/kjpp.2018.22.4.427_ref19) 2013; 2013 Bakhtiari (10.4196/kjpp.2018.22.4.427_ref59) 2015; 85 Tsai (10.4196/kjpp.2018.22.4.427_ref22) 2008; 73 Chu (10.4196/kjpp.2018.22.4.427_ref52) 2015; 59 Bamman (10.4196/kjpp.2018.22.4.427_ref10) 2018; 8 Li (10.4196/kjpp.2018.22.4.427_ref43) 2017; 101 Ullevig (10.4196/kjpp.2018.22.4.427_ref23) 2011; 219 Choi (10.4196/kjpp.2018.22.4.427_ref29) 2000; 17 Stockinger (10.4196/kjpp.2018.22.4.427_ref48) 2017; 73 Ogasawara (10.4196/kjpp.2018.22.4.427_ref57) 2016; 6 Arthur (10.4196/kjpp.2018.22.4.427_ref60) 2012; 8 Park (10.4196/kjpp.2018.22.4.427_ref42) 2009; 105 Kunkel (10.4196/kjpp.2018.22.4.427_ref24) 2011; 13 Bang (10.4196/kjpp.2018.22.4.427_ref25) 2014; 18 Lai (10.4196/kjpp.2018.22.4.427_ref11) 2018; 47 Liu (10.4196/kjpp.2018.22.4.427_ref36) 2013; 8 Kim (10.4196/kjpp.2018.22.4.427_ref37) 2011; 45 Kunkel (10.4196/kjpp.2018.22.4.427_ref27) 2012; 7 Coutinho (10.4196/kjpp.2018.22.4.427_ref33) 2002; 35 Spiegelman (10.4196/kjpp.2018.22.4.427_ref50) 2001; 104 Fan (10.4196/kjpp.2018.22.4.427_ref47) 2017; 25 Brotto (10.4196/kjpp.2018.22.4.427_ref8) 2012; 343 Ruuskanen (10.4196/kjpp.2018.22.4.427_ref16) 1995; 24 7543366 - Cancer Lett. 1995 Aug 1;94(2):213-8 11239410 - Cell. 2001 Feb 23;104(4):531-43 21752377 - Atherosclerosis. 2011 Dec;219(2):409-16 29471456 - Age Ageing. 2018 May 1;47(3):367-373 25976755 - Med Hypotheses. 2015 Jul;85(1):1-6 19213934 - J Appl Physiol (1985). 2009 Apr;106(4):1072-8 28473056 - Nutr Res. 2017 Apr;40:1-20 27331824 - J Am Coll Nutr. 2016 Sep-Oct;35(7):627-638 24900000 - Nucl Med Mol Imaging. 2011 Sep;45(3):169-76 23372143 - J Appl Physiol (1985). 2013 Apr;114(7):934-40 28250722 - Prz Menopauzalny. 2016 Dec;15(4):193-201 28490543 - Cold Spring Harb Perspect Med. 2018 Jun 1;8(6) 26338703 - J Biol Chem. 2015 Oct 16;290(42):25497-511 28329051 - J Gerontol A Biol Sci Med Sci. 2017 Dec 12;73(1):21-28 9390967 - J Appl Physiol (1985). 1997 Dec;83(6):1947-53 21680879 - J Appl Physiol (1985). 2011 Sep;111(3):834-43 27502839 - Sci Rep. 2016 Aug 09;6:31142 22935006 - Geriatr Gerontol Int. 2013 Apr;13(2):458-65 19696408 - Circ Res. 2009 Sep 25;105(7):705-12, 11 p following 712 26578969 - Front Physiol. 2015 Oct 27;6:296 29225311 - J Nutr Sci Vitaminol (Tokyo). 2017;63(5):277-283 15583801 - Oncol Rep. 2005 Jan;13(1):51-7 25944715 - Mol Nutr Food Res. 2015 Aug;59(8):1491-503 10938399 - Int J Oncol. 2000 Sep;17(3):565-71 18587128 - J Exp Biol. 2008 Jul;211(Pt 14):2336-45 16770348 - Appl Physiol Nutr Metab. 2006 Jun;31(3):218-25 7493202 - J Gerontol A Biol Sci Med Sci. 1995 Nov;50 Spec No:11-6 24304680 - Clin Physiol Funct Imaging. 2014 Nov;34(6):463-70 18674809 - Cell. 2008 Aug 8;134(3):405-15 536299 - J Appl Physiol Respir Environ Exerc Physiol. 1979 Dec;47(6):1278-83 8425294 - Circulation. 1993 Feb;87(2):470-5 7484485 - Age Ageing. 1995 Jul;24(4):292-6 18203131 - Mol Nutr Food Res. 2008 Jan;52(1):26-42 18946072 - N Engl J Med. 2008 Oct 23;359(17):1842-4 26658171 - Pharmacol Res. 2016 Jan;103:158-66 21846575 - Lancet. 2011 Oct 1;378(9798):1244-53 11797013 - Nature. 2002 Jan 17;415(6869):339-43 25502801 - Gerontology. 2015;61(2):139-48 24917153 - Muscle Nerve. 2015 Mar;51(3):391-9 23484095 - Biomed Res Int. 2013;2013:218970 18803714 - J Food Sci. 2008 Sep;73(7):H174-8 27727454 - Clin Pharmacol Ther. 2017 Feb;101(2):188-190 21612453 - J Med Food. 2011 Nov;14(11):1375-82 27999607 - Evid Based Complement Alternat Med. 2016;2016:4301621 27889389 - Cell Metab. 2017 Feb 7;25(2):242-247 26331671 - J Med Food. 2015 Dec;18(12):1380-6 18812460 - Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1181-90 22929991 - J Pharmacol Exp Ther. 2012 Dec;343(3):540-6 22745735 - PLoS One. 2012;7(6):e39332 21641545 - Cell Metab. 2011 Jun 8;13(6):627-38 11509493 - J Appl Physiol (1985). 2001 Sep;91(3):1017-28 3366726 - J Appl Physiol (1985). 1988 Mar;64(3):1038-44 16054041 - Cell Metab. 2005 Jan;1(1):15-25 25330387 - PLoS One. 2014 Oct 17;9(10):e110020 22565934 - Circulation. 2012 Jun 5;125(22):2716-27 12426632 - Braz J Med Biol Res. 2002 Nov;35(11):1329-32 2342214 - JAMA. 1990 Jun 13;263(22):3029-34 28675237 - Food Funct. 2017 Jul 19;8(7):2425-2436 23900420 - Am J Physiol Endocrinol Metab. 2013 Sep 15;305(6):E760-5 22701343 - Int J Biol Sci. 2012;8(5):731-60 15219842 - Biochem Biophys Res Commun. 2004 Jul 23;320(2):402-8 25206561 - Neural Regen Res. 2013 Sep 25;8(27):2510-9 12907607 - Cancer Res. 2003 Aug 1;63(15):4375-83 25352765 - Korean J Physiol Pharmacol. 2014 Oct;18(5):441-6 26243357 - Osteoporos Int. 2016 Feb;27(2):473-82 28286988 - Climacteric. 2017 Apr;20(2):119-124 10995596 - Clin Sci (Lond). 2000 Oct;99(4):309-14 |
| References_xml | – volume: 51 start-page: 391 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref38 publication-title: Muscle Nerve doi: 10.1002/mus.24316 – volume: 1 start-page: 15 year: 2005 ident: 10.4196/kjpp.2018.22.4.427_ref54 publication-title: Cell Metab doi: 10.1016/j.cmet.2004.12.003 – volume: 85 start-page: 1 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref59 publication-title: Med Hypotheses doi: 10.1016/j.mehy.2015.02.014 – volume: 63 start-page: 277 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref40 publication-title: J Nutr Sci Vitaminol (Tokyo) doi: 10.3177/jnsv.63.277 – volume: 378 start-page: 1244 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref18 publication-title: Lancet doi: 10.1016/S0140-6736(11)60749-6 – volume: 35 start-page: 627 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref66 publication-title: J Am Coll Nutr doi: 10.1080/07315724.2015.1132019 – volume: 104 start-page: 531 year: 2001 ident: 10.4196/kjpp.2018.22.4.427_ref50 publication-title: Cell doi: 10.1016/S0092-8674(01)00240-9 – volume: 59 start-page: 1491 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref52 publication-title: Mol Nutr Food Res doi: 10.1002/mnfr.201400670 – volume: 13 start-page: 627 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref24 publication-title: Cell Metab doi: 10.1016/j.cmet.2011.03.020 – volume: 40 start-page: 1 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref49 publication-title: Nutr Res doi: 10.1016/j.nutres.2017.01.001 – volume: 94 start-page: 213 year: 1995 ident: 10.4196/kjpp.2018.22.4.427_ref32 publication-title: Cancer Lett doi: 10.1016/0304-3835(95)03856-R – volume: 103 start-page: 158 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref45 publication-title: Pharmacol Res doi: 10.1016/j.phrs.2015.11.009 – volume: 219 start-page: 409 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref23 publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2011.06.013 – volume: 91 start-page: 1017 year: 2001 ident: 10.4196/kjpp.2018.22.4.427_ref53 publication-title: J Appl Physiol (1985) doi: 10.1152/jappl.2001.91.3.1017 – volume: 73 start-page: H174 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref22 publication-title: J Food Sci doi: 10.1111/j.1750-3841.2008.00864.x – volume: 13 start-page: 51 year: 2005 ident: 10.4196/kjpp.2018.22.4.427_ref28 publication-title: Oncol Rep – volume: 320 start-page: 402 year: 2004 ident: 10.4196/kjpp.2018.22.4.427_ref31 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2004.05.183 – volume: 6 start-page: 31142 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref57 publication-title: Sci Rep doi: 10.1038/srep31142 – volume: 8 start-page: 731 year: 2012 ident: 10.4196/kjpp.2018.22.4.427_ref60 publication-title: Int J Biol Sci doi: 10.7150/ijbs.4262 – volume: 8 start-page: 2510 year: 2013 ident: 10.4196/kjpp.2018.22.4.427_ref36 publication-title: Neural Regen Res – volume: 134 start-page: 405 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref44 publication-title: Cell doi: 10.1016/j.cell.2008.06.051 – volume: 61 start-page: 139 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref62 publication-title: Gerontology doi: 10.1159/000365947 – volume: 295 start-page: E1181 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref34 publication-title: Am J Physiol Endocrinol Metab doi: 10.1152/ajpendo.90532.2008 – volume: 7 start-page: e39332 year: 2012 ident: 10.4196/kjpp.2018.22.4.427_ref27 publication-title: PLoS One doi: 10.1371/journal.pone.0039332 – volume: 17 start-page: 565 year: 2000 ident: 10.4196/kjpp.2018.22.4.427_ref29 publication-title: Int J Oncol – volume: 50 start-page: 11 year: 1995 ident: 10.4196/kjpp.2018.22.4.427_ref63 publication-title: J Gerontol A Biol Sci Med Sci – volume: 8 start-page: a029751 year: 2018 ident: 10.4196/kjpp.2018.22.4.427_ref10 publication-title: Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a029751 – volume: 18 start-page: 149 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref35 publication-title: Basic Applied Myology – volume: 45 start-page: 169 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref37 publication-title: Nucl Med Mol Imaging doi: 10.1007/s13139-011-0087-7 – volume: 415 start-page: 339 year: 2002 ident: 10.4196/kjpp.2018.22.4.427_ref55 publication-title: Nature doi: 10.1038/415339a – volume: 263 start-page: 3029 year: 1990 ident: 10.4196/kjpp.2018.22.4.427_ref14 publication-title: JAMA doi: 10.1001/jama.1990.03440220053029 – volume: 9 start-page: e110020 year: 2014 ident: 10.4196/kjpp.2018.22.4.427_ref61 publication-title: PLoS One doi: 10.1371/journal.pone.0110020 – volume: 359 start-page: 1842 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref17 publication-title: N Engl J Med doi: 10.1056/NEJMcibr0806723 – volume: 13 start-page: 458 year: 2013 ident: 10.4196/kjpp.2018.22.4.427_ref7 publication-title: Geriatr Gerontol Int doi: 10.1111/j.1447-0594.2012.00923.x – volume: 2016 start-page: 4301621 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref67 publication-title: Evid Based Complement Alternat Med doi: 10.1155/2016/4301621 – volume: 64 start-page: 1038 year: 1988 ident: 10.4196/kjpp.2018.22.4.427_ref13 publication-title: J Appl Physiol (1985) doi: 10.1152/jappl.1988.64.3.1038 – volume: 2013 start-page: 218970 year: 2013 ident: 10.4196/kjpp.2018.22.4.427_ref19 publication-title: Biomed Res Int doi: 10.1155/2013/218970 – volume: 15 start-page: 193 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref58 publication-title: Prz Menopauzalny – volume: 343 start-page: 540 year: 2012 ident: 10.4196/kjpp.2018.22.4.427_ref8 publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.112.191759 – volume: 106 start-page: 1072 year: 2009 ident: 10.4196/kjpp.2018.22.4.427_ref41 publication-title: J Appl Physiol (1985) doi: 10.1152/japplphysiol.91566.2008 – volume: 14 start-page: 1375 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref51 publication-title: J Med Food doi: 10.1089/jmf.2010.0267 – volume: 47 start-page: 367 year: 2018 ident: 10.4196/kjpp.2018.22.4.427_ref11 publication-title: Age Ageing doi: 10.1093/ageing/afy009 – volume: 18 start-page: 441 year: 2014 ident: 10.4196/kjpp.2018.22.4.427_ref25 publication-title: Korean J Physiol Pharmacol doi: 10.4196/kjpp.2014.18.5.441 – volume: 99 start-page: 309 year: 2000 ident: 10.4196/kjpp.2018.22.4.427_ref5 publication-title: Clin Sci (Lond) doi: 10.1042/cs0990309 – volume: 18 start-page: 1380 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref26 publication-title: J Med Food doi: 10.1089/jmf.2014.3401 – volume: 25 start-page: 242 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref47 publication-title: Cell Metab doi: 10.1016/j.cmet.2016.10.022 – volume: 20 start-page: 119 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref15 publication-title: Climacteric doi: 10.1080/13697137.2017.1286890 – volume: 111 start-page: 834 year: 2011 ident: 10.4196/kjpp.2018.22.4.427_ref3 publication-title: J Appl Physiol (1985) doi: 10.1152/japplphysiol.00031.2011 – volume: 114 start-page: 934 year: 2013 ident: 10.4196/kjpp.2018.22.4.427_ref56 publication-title: J Appl Physiol (1985) doi: 10.1152/japplphysiol.01161.2012 – volume: 31 start-page: 218 year: 2006 ident: 10.4196/kjpp.2018.22.4.427_ref20 publication-title: Appl Physiol Nutr Metab doi: 10.1139/h05-028 – volume: 27 start-page: 473 year: 2016 ident: 10.4196/kjpp.2018.22.4.427_ref6 publication-title: Osteoporos Int doi: 10.1007/s00198-015-3241-8 – volume: 34 start-page: 463 year: 2014 ident: 10.4196/kjpp.2018.22.4.427_ref12 publication-title: Clin Physiol Funct Imaging doi: 10.1111/cpf.12117 – volume: 52 start-page: 26 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref30 publication-title: Mol Nutr Food Res doi: 10.1002/mnfr.200700389 – volume: 125 start-page: 2716 year: 2012 ident: 10.4196/kjpp.2018.22.4.427_ref9 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.111.047381 – volume: 101 start-page: 188 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref43 publication-title: Clin Pharmacol Ther doi: 10.1002/cpt.533 – volume: 63 start-page: 4375 year: 2003 ident: 10.4196/kjpp.2018.22.4.427_ref21 publication-title: Cancer Res – volume: 6 start-page: 296 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref46 publication-title: Front Physiol doi: 10.3389/fphys.2015.00296 – volume: 47 start-page: 1278 year: 1979 ident: 10.4196/kjpp.2018.22.4.427_ref39 publication-title: J Appl Physiol Respir Environ Exerc Physiol – volume: 305 start-page: E760 year: 2013 ident: 10.4196/kjpp.2018.22.4.427_ref65 publication-title: Am J Physiol Endocrinol Metab doi: 10.1152/ajpendo.00302.2013 – volume: 290 start-page: 25497 year: 2015 ident: 10.4196/kjpp.2018.22.4.427_ref1 publication-title: J Biol Chem doi: 10.1074/jbc.M115.681445 – volume: 24 start-page: 292 year: 1995 ident: 10.4196/kjpp.2018.22.4.427_ref16 publication-title: Age Ageing doi: 10.1093/ageing/24.4.292 – volume: 105 start-page: 705 year: 2009 ident: 10.4196/kjpp.2018.22.4.427_ref42 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.109.205310 – volume: 73 start-page: 21 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref48 publication-title: J Gerontol A Biol Sci Med Sci doi: 10.1093/gerona/glx023 – volume: 8 start-page: 2425 year: 2017 ident: 10.4196/kjpp.2018.22.4.427_ref68 publication-title: Food Funct doi: 10.1039/C7FO00127D – volume: 211 start-page: 2336 year: 2008 ident: 10.4196/kjpp.2018.22.4.427_ref64 publication-title: J Exp Biol doi: 10.1242/jeb.017640 – volume: 87 start-page: 470 year: 1993 ident: 10.4196/kjpp.2018.22.4.427_ref4 publication-title: Circulation doi: 10.1161/01.CIR.87.2.470 – volume: 35 start-page: 1329 year: 2002 ident: 10.4196/kjpp.2018.22.4.427_ref33 publication-title: Braz J Med Biol Res doi: 10.1590/S0100-879X2002001100010 – volume: 83 start-page: 1947 year: 1997 ident: 10.4196/kjpp.2018.22.4.427_ref2 publication-title: J Appl Physiol (1985) doi: 10.1152/jappl.1997.83.6.1947 – reference: 28329051 - J Gerontol A Biol Sci Med Sci. 2017 Dec 12;73(1):21-28 – reference: 26243357 - Osteoporos Int. 2016 Feb;27(2):473-82 – reference: 26338703 - J Biol Chem. 2015 Oct 16;290(42):25497-511 – reference: 15583801 - Oncol Rep. 2005 Jan;13(1):51-7 – reference: 24917153 - Muscle Nerve. 2015 Mar;51(3):391-9 – reference: 24304680 - Clin Physiol Funct Imaging. 2014 Nov;34(6):463-70 – reference: 18812460 - Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1181-90 – reference: 22745735 - PLoS One. 2012;7(6):e39332 – reference: 11509493 - J Appl Physiol (1985). 2001 Sep;91(3):1017-28 – reference: 24900000 - Nucl Med Mol Imaging. 2011 Sep;45(3):169-76 – reference: 18674809 - Cell. 2008 Aug 8;134(3):405-15 – reference: 27727454 - Clin Pharmacol Ther. 2017 Feb;101(2):188-190 – reference: 26658171 - Pharmacol Res. 2016 Jan;103:158-66 – reference: 18587128 - J Exp Biol. 2008 Jul;211(Pt 14):2336-45 – reference: 28286988 - Climacteric. 2017 Apr;20(2):119-124 – reference: 10995596 - Clin Sci (Lond). 2000 Oct;99(4):309-14 – reference: 7493202 - J Gerontol A Biol Sci Med Sci. 1995 Nov;50 Spec No:11-6 – reference: 3366726 - J Appl Physiol (1985). 1988 Mar;64(3):1038-44 – reference: 23372143 - J Appl Physiol (1985). 2013 Apr;114(7):934-40 – reference: 15219842 - Biochem Biophys Res Commun. 2004 Jul 23;320(2):402-8 – reference: 21752377 - Atherosclerosis. 2011 Dec;219(2):409-16 – reference: 23900420 - Am J Physiol Endocrinol Metab. 2013 Sep 15;305(6):E760-5 – reference: 11239410 - Cell. 2001 Feb 23;104(4):531-43 – reference: 11797013 - Nature. 2002 Jan 17;415(6869):339-43 – reference: 18803714 - J Food Sci. 2008 Sep;73(7):H174-8 – reference: 28250722 - Prz Menopauzalny. 2016 Dec;15(4):193-201 – reference: 25330387 - PLoS One. 2014 Oct 17;9(10):e110020 – reference: 25976755 - Med Hypotheses. 2015 Jul;85(1):1-6 – reference: 21641545 - Cell Metab. 2011 Jun 8;13(6):627-38 – reference: 25206561 - Neural Regen Res. 2013 Sep 25;8(27):2510-9 – reference: 21612453 - J Med Food. 2011 Nov;14(11):1375-82 – reference: 16054041 - Cell Metab. 2005 Jan;1(1):15-25 – reference: 7484485 - Age Ageing. 1995 Jul;24(4):292-6 – reference: 19696408 - Circ Res. 2009 Sep 25;105(7):705-12, 11 p following 712 – reference: 21846575 - Lancet. 2011 Oct 1;378(9798):1244-53 – reference: 25944715 - Mol Nutr Food Res. 2015 Aug;59(8):1491-503 – reference: 23484095 - Biomed Res Int. 2013;2013:218970 – reference: 19213934 - J Appl Physiol (1985). 2009 Apr;106(4):1072-8 – reference: 26331671 - J Med Food. 2015 Dec;18(12):1380-6 – reference: 536299 - J Appl Physiol Respir Environ Exerc Physiol. 1979 Dec;47(6):1278-83 – reference: 21680879 - J Appl Physiol (1985). 2011 Sep;111(3):834-43 – reference: 22935006 - Geriatr Gerontol Int. 2013 Apr;13(2):458-65 – reference: 26578969 - Front Physiol. 2015 Oct 27;6:296 – reference: 12426632 - Braz J Med Biol Res. 2002 Nov;35(11):1329-32 – reference: 27502839 - Sci Rep. 2016 Aug 09;6:31142 – reference: 28490543 - Cold Spring Harb Perspect Med. 2018 Jun 1;8(6): – reference: 27999607 - Evid Based Complement Alternat Med. 2016;2016:4301621 – reference: 29471456 - Age Ageing. 2018 May 1;47(3):367-373 – reference: 18946072 - N Engl J Med. 2008 Oct 23;359(17):1842-4 – reference: 9390967 - J Appl Physiol (1985). 1997 Dec;83(6):1947-53 – reference: 28675237 - Food Funct. 2017 Jul 19;8(7):2425-2436 – reference: 16770348 - Appl Physiol Nutr Metab. 2006 Jun;31(3):218-25 – reference: 8425294 - Circulation. 1993 Feb;87(2):470-5 – reference: 27331824 - J Am Coll Nutr. 2016 Sep-Oct;35(7):627-638 – reference: 7543366 - Cancer Lett. 1995 Aug 1;94(2):213-8 – reference: 18203131 - Mol Nutr Food Res. 2008 Jan;52(1):26-42 – reference: 2342214 - JAMA. 1990 Jun 13;263(22):3029-34 – reference: 22929991 - J Pharmacol Exp Ther. 2012 Dec;343(3):540-6 – reference: 27889389 - Cell Metab. 2017 Feb 7;25(2):242-247 – reference: 28473056 - Nutr Res. 2017 Apr;40:1-20 – reference: 29225311 - J Nutr Sci Vitaminol (Tokyo). 2017;63(5):277-283 – reference: 22701343 - Int J Biol Sci. 2012;8(5):731-60 – reference: 12907607 - Cancer Res. 2003 Aug 1;63(15):4375-83 – reference: 10938399 - Int J Oncol. 2000 Sep;17(3):565-71 – reference: 25502801 - Gerontology. 2015;61(2):139-48 – reference: 22565934 - Circulation. 2012 Jun 5;125(22):2716-27 – reference: 25352765 - Korean J Physiol Pharmacol. 2014 Oct;18(5):441-6 |
| SSID | ssib008505809 ssj0064464 |
| Score | 2.2551847 |
| Snippet | The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the... |
| SourceID | nrf pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 427 |
| SubjectTerms | Original 약리학 |
| Title | Concurrent treatment with ursolic acid and low-intensity treadmill exercise improves muscle atrophy and related outcomes in rats |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/29962857 https://www.proquest.com/docview/2063710061 https://pubmed.ncbi.nlm.nih.gov/PMC6019874 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002369294 |
| Volume | 22 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | The Korean Journal of Physiology & Pharmacology, 2018, 22(4), , pp.427-436 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLa68cILAsal3GQQ4iVKSRzn0setAsYmJh42UZ6sxHXW0i2u2kYInvhj_DfOiR33wkCMl7RKnOOm58vJ55Pjz4S8VDJWJTI3FsSBzxlP_SLLR_4oU4FMw7xv3ph-OEkOz_jRMB52Oj_XqpbqZdGT36-cV_I_XoV94FecJXsNzzqjsAO-g39hCx6G7T_5eKArafWVVgXjTWa1xmWwUYpVThotVu9Cf_UnplwdaDe2HuGCQ27JJZwuOdcoQXtZL6AbD3Pk4AJTf44Vc8BMdb2Ey2hKuDxAzmKd2SLejvW8TexbktskTozME2JsthLKdql8u57zUa68wVhpV_FxbDPZn2uMaNrNKDrRYzNDp_IOJi5BZFK-B7maep-0hZpNZoSZK3xt4y-wQZ_HtrJaNftY0I_8KDMSAm3QZmwNnHwtAnPTbvvJwCHSgDunX2YoUhpmPcZ6vGcbb8pwbz0eXdEiDJfQikAbAm0IxgQXYGOH3GBp2lQJvBuuwmUG7LJRRzPEAJhno2bmrtHM4UKbr3__XRs8aaeal1cNgbYredeo0eltcsuOaei-Aegd0lHVXbK3X-VLffmNvqIfHQj2yI8VZqnDLEXMUotZipilADu6gVnqMEtbzNIWs9RgllrMNidbzNIWs3RSUcTsPXL29s3p4NC3q4D4kkfJ0mdZWUiZxUDmYhjdJkWqSpVxBc8imSY8k3h8lKexGkVAltNEsbIfB0mZsiQukiC6T3YrXamHhKqCsVClYQhsg0fBqM8LFaRS8aDIWJznXRK2_7mQViIfV2q5EH_2fZd47pyZEYj5a-sX4EoxlROBuu74ea7FdC5g9PpeRDC8AIx0yfPW0wKCPb7Byyul6wXYSiKU40rCLnlgPO86BV6J06Ghi3QDE64Bdrh5pJqMG0H5JMDUI390rUt5TG6u7uAnZHc5r9VTIOjL4llzG_wCfcvrVA |
| linkProvider | Geneva Foundation for Medical Education and Research |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Concurrent+treatment+with+ursolic+acid+and+low-intensity+treadmill+exercise+improves+muscle+atrophy+and+related+outcomes+in+rats&rft.jtitle=The+Korean+journal+of+physiology+%26+pharmacology&rft.au=Kim%2C+Jae+Cheol&rft.au=Kang%2C+Yun+Seok&rft.au=Noh%2C+Eun+Bi&rft.au=Seo%2C+Baek+Woon&rft.date=2018-07-01&rft.issn=1226-4512&rft.eissn=2093-3827&rft.volume=22&rft.issue=4&rft.spage=427&rft_id=info:doi/10.4196%2Fkjpp.2018.22.4.427&rft.externalDBID=n%2Fa&rft.externalDocID=10_4196_kjpp_2018_22_4_427 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1226-4512&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1226-4512&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1226-4512&client=summon |