The investigation of genetic polymorphisms in the carbonic anhydrase VI gene exon 2 and salivary parameters in type 2 diabetic patients and healthy adults

• Published in: Molecular biology reports Vol. 39; no. 5; pp. 5677 - 5682
• Main Authors: Koç Öztürk, Leyla, Ulucan, Korkut, Akyüz, Serap, Furuncuoğlu, Halit, Bayer, Hikmet, Yarat, Ayşen
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.05.2012; Springer Nature B.V
• Subjects: Adult; adults; Aged; Amino acid sequence; amino acids; Animal Anatomy; Animal Biochemistry; Base Sequence; Biomedical and Life Sciences; blood; Blood Glucose - metabolism; Body fluids; buffering capacity; Carbonate dehydratase; Carbonic Anhydrases - genetics; Case-Control Studies; Dental caries; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - enzymology; Diabetes Mellitus, Type 2 - genetics; DNA sequencing; Enzymes; Exons; Exons - genetics; Female; Gene polymorphism; Genetic Predisposition to Disease; Genotyping Techniques; Glycated Hemoglobin A - metabolism; Health; Histology; Humans; Life Sciences; Male; Middle Aged; Molecular biology; Molecular Sequence Data; Morphology; noninsulin-dependent diabetes mellitus; patients; pH effects; Polymerase chain reaction; Polymorphism; Polymorphism, Single Nucleotide - genetics; Saliva; Saliva - metabolism; sequence analysis; Single-nucleotide polymorphism; Teeth; Young Adult; Type 2 diabetes; Gene; Saliva; Carbonic anhydrase VI; Polymorphism

The aim of this study was to investigate carbonic anhydrase (CA) VI Exon 2 single nucleotide polymorphism (SNP) and its possible association with salivary parameters in type 2 diabetic patients compared to healthy adults. Caries status was measured by using the DMFT (number of decayed, missing, and...