Pathophysiology of Age-Related Macular Degeneration: Implications for Treatment

• Published in: Ophthalmic research Vol. 65; no. 6; pp. 615 - 636
• Main Authors: Garcia-Garcia, Julián, Usategui-Martin, Ricardo, Sanabria, Maria Rosa, Fernandez-Perez, Esther, Telleria, Juan Jose, Coco-Martin, Rosa M.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.12.2022
• Subjects: Antioxidants; Development and progression; Drug therapy; Epigenetic inheritance; Genetic polymorphisms; High-Temperature Requirement A Serine Peptidase 1; Humans; Inflammation; Lipids; Macular degeneration; Macular Degeneration - genetics; Physiological aspects; Proteins; Review Article; Spain; Epigenetics; Oxidative stress; Complement; Pathophysiology; Age-related macular degeneration

Abstract Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal disease that affects millions of people worldwide and has become the leading cause of visual impairment in developed countries. The disease etiopathogenesis is not understood fully, although many trigge...