A method to study sustained antimicrobial activity of rinse and dentifrice components on biofilm viability in vivo

• Published in: Journal of clinical periodontology Vol. 33; no. 1; pp. 14 - 20
• Main Authors: Van Der Mei, H. C., White, D. J., Atema-Smit, J., Van De Belt-Gritter, E., Busscher, H. J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Munksgaard International Publishers 01.01.2006
• Subjects: Anti-Infective Agents, Local - pharmacology; Anti-Infective Agents, Local - therapeutic use; Biofilms - drug effects; Chlorhexidine - pharmacology; Chlorhexidine - therapeutic use; chlorhexidine mouth rinse; confocal scanning laser microscopy; Dental Plaque - microbiology; Dental Plaque - prevention & control; dentifrices; Dentifrices - pharmacology; Dentifrices - therapeutic use; Dentistry; Humans; Microbial Viability - drug effects; Microscopy, Confocal; Mouthwashes - pharmacology; Mouthwashes - therapeutic use; Outcome Assessment (Health Care) - methods; plaque; Research Design; substantivity; Tin Fluorides - pharmacology; Tin Fluorides - therapeutic use

Aim: To develop an improved method for quantitative assessment of antimicrobial efficacy and substantivity of mouth rinses and dentifrices on in vivo treated plaque. Material and Methods: Nine‐ and 72‐h‐old plaques were formed in volunteers carrying out standardized hygiene using NaF‐containing dent...