Cytoskeletal protein abnormalities in patients with olivopontocerebellar atrophy--an immunocytochemical and Gallyas silver impregnation study

• Published in: Neuropathology and applied neurobiology Vol. 18; no. 3; p. 237
• Main Authors: Kobayashi, K, Miyazu, K, Katsukawa, K, Fukutani, Y, Mukai, M, Nakamura, I, Yamaguchi, N, Matsubara, R, Isaki, K
• Format: Journal Article
• Language: English
• Published: England 01.06.1992
• Subjects: Aged; Cytoskeletal Proteins - analysis; Cytoskeletal Proteins - metabolism; Female; Humans; Immunoenzyme Techniques; Immunohistochemistry; Male; Middle Aged; Nerve Fibers - ultrastructure; Nerve Tissue Proteins - analysis; Nerve Tissue Proteins - metabolism; Nervous System Diseases - pathology; Oligodendroglia - ultrastructure; Olivopontocerebellar Atrophies - metabolism; Olivopontocerebellar Atrophies - pathology; Silver Staining
• ISSN: 0305-1846
• DOI: 10.1111/j.1365-2990.1992.tb00786.x

A highly sensitive silver technique for glial cytoplasmic inclusions (GCI) in olivopontocerebellar atrophy (OPCA) was applied to tissues from 15 patients with neurodegenerative disorders including OPCA, Joseph disease, Alzheimer's disease (AD), Huntington's chorea, Pick disease and three c...