Polymorphism of the SLB serologically defined (non-MHC) alloantigenic system in pigs

Six new antigenic specificities (designated SLB-2 to SLB-7) detectable with polyclonal reagents in the complement-dependent lymphocytotoxic test were determined in the SLB alloantigenic system of pigs. The SLB specificities (including the previously described SLB-1) are controlled by 13 alleles. An...

Full description

Saved in:
Bibliographic Details
Published inAnimal genetics Vol. 19; no. 3; p. 285
Main Authors Hruban, V, Hradecký, J, Dvorák, P
Format Journal Article
LanguageEnglish
Published England 01.01.1988
Subjects
Alleles
Animals
Crosses, Genetic
Epitopes - genetics
Lod Score
Polymorphism, Genetic
Swine - genetics
Swine - immunology
Online AccessGet more information

Cover

More Information
Summary:Six new antigenic specificities (designated SLB-2 to SLB-7) detectable with polyclonal reagents in the complement-dependent lymphocytotoxic test were determined in the SLB alloantigenic system of pigs. The SLB specificities (including the previously described SLB-1) are controlled by 13 alleles. An analysis of a further 121 double backcross matings (with 817 offspring) confirmed that the products of SLB alleles segregated independently of the SLA haplotypes (swine MHC). In addition, in 112 families of the same mating type (with 746 progeny) the map distance of the SLB locus and the highly polymorphic L blood group locus was found to be 7.82 centimorgans in the heterogametic sex and 12.57 centimorgans in the homogametic sex.
ISSN:0268-9146
1365-2052
DOI:10.1111/j.1365-2052.1988.tb00817.x