Association Among Serum Fetuin-A Level, Coronary Artery Calcification, and Bone Mineral Densitometry in Maintenance Hemodialysis Patients

• Published in: Artificial organs Vol. 33; no. 10; pp. 844 - 854
• Main Authors: Kirkpantur, Alper, Altun, Bulent, Hazirolan, Tuncay, Akata, Deniz, Arici, Mustafa, Kirazli, Serafettin, Turgan, Cetin
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.10.2009
• Subjects: Absorptiometry, Photon; Adult; Aged; alpha-2-HS-Glycoprotein; Biomarkers - blood; Blood Proteins - analysis; Bone Density; Bone mineral density; Calcinosis - blood; Calcinosis - diagnostic imaging; Calcinosis - etiology; Case-Control Studies; Coronary artery calcification; Coronary Artery Disease - blood; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - etiology; Cross-Sectional Studies; Female; Fetuin-A; Hemodialysis; Hip Joint - diagnostic imaging; Humans; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - diagnostic imaging; Kidney Failure, Chronic - therapy; Lumbar Vertebrae - diagnostic imaging; Male; Middle Aged; Proportional Hazards Models; Radius - diagnostic imaging; Renal Dialysis; Risk Assessment; Risk Factors; Severity of Illness Index; Tomography, X-Ray Computed

Patients with end‐stage renal disease have a very high prevalance and extent of arterial calcification. A number of studies suggest that similar pathophysiologic mechanisms are responsible for development and progression of calcification of atherosclerotic plaque and bone formation. Fetuin‐A is a po...