Pharmacokinetics of intravenous, intrathecal and epidural morphine and fentanyl in the goat

• Published in: Acta anaesthesiologica Scandinavica Vol. 30; no. 5; p. 393
• Main Authors: Andersen, H B, Christensen, B, Findlay, J W, Jansen, J A
• Format: Journal Article
• Language: English
• Published: England 01.07.1986
• Subjects: Animals; Fentanyl - administration & dosage; Fentanyl - metabolism; Goats; Injections, Epidural; Injections, Intravenous; Injections, Spinal; Kinetics; Morphine - administration & dosage; Morphine - metabolism

Intrathecal and epidural catheters and an intravenous cannula were inserted in 10 goats. After administration of either morphine 4 mg, intravenously, 1 mg intrathecally or 4 and 8 mg epidurally, or fentanyl 0.1 mg intravenously, 0.05 mg intrathecally or 0.1 and 0.2 mg epidurally, venous blood and CS...