Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro

• Published in: Cancer management and research Vol. 13; pp. 3685 - 3697
• Main Authors: Li, Chun-Yan, Chen, Chun-Ya, An, Jian-Hong, Wu, Jian-Bin, Shen, Hong
• Format: Journal Article
• Language: English
• Published: New Zealand Taylor & Francis Ltd 2021; Dove; Dove Medical Press
• Subjects: Antibodies; Bladder cancer; Cell adhesion & migration; Cervical cancer; Extracellular matrix; invasion; Medical prognosis; migration; normal basal epithelial cells; Original Research; Phosphorylation; Pore size; Prostate cancer; rm-1; stat3; tgf-β1; Wound healing; United States > US; China; normal basal epithelial cells; migration; RM-1; TGF-β1; invasion; STAT3

Basal epithelial cells are absent in distant prostate cancer. This study aimed to investigate whether basal epithelial cells could suppress migration and invasion of prostate cancer cells to become a new treatment strategy for prostate cancer. Basal epithelial cells were identified by immunofluoresc...