Association of Metformin Use With End-Stage Renal Disease in Patients With Type 2 Diabetes Mellitus: A Nationwide Cohort Study Under the Pay-for-Performance Program

• Published in: Journal of clinical pharmacology Vol. 59; no. 11; p. 1443
• Main Authors: Lee, Ming-Chia, Lee, Chih-Hsin, Chang, Lih-Yu, Chang, Chia-Hao, Zhang, Jun-Fu, Lee, Meng-Rui, Wang, Jann-Yuan, Chen, Shih-Ming
• Format: Journal Article
• Language: English
• Published: England 01.11.2019
• Subjects: metformin; chronic kidney disease; diabetes mellitus; end-stage renal disease; propensity score

Animal studies have demonstrated that metformin exerts a renoprotective effect. Human studies of patients with diabetes mellitus (DM) regarding the association of metformin use with end-stage renal disease (ESRD) are lacking. Patients with type 2 DM and without a history of kidney disease who were e...