Neuronal cells from bipolar individuals are more susceptible to glutamate induced apoptosis than cells from non-bipolar subjects

• Published in: Journal of affective disorders Vol. 294; pp. 568 - 573
• Main Authors: Hu, Ming, Gao, Yonglin, El-Mallakh, Rif S
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.11.2021
• Subjects: Apoptosis; Bipolar disorder; Glutamate; Lithium; Olfactory neuroepithelial progenitors; Psychiatric/Mental Health; Bipolar disorder; Lithium; Olfactory neuroepithelial progenitors; Glutamate; Apoptosis; lithium; apoptosis; bipolar disorder; glutamate; olfactory neuroepithelial progenitors

•Olfactory neuroepithelial progenitor (ONP) cells are a novel cellular model that allows for the examination of neuronal cellular physiology with the preservation of disease-specific physiology.•ONPs derived from individuals with bipolar type I illness are more susceptible to glutamate induced apopt...