Neuroimaging-aided differential diagnosis of the depressive state

• Published in: NeuroImage (Orlando, Fla.) Vol. 85; pp. 498 - 507
• Main Authors: Takizawa, Ryu, Fukuda, Masato, Kawasaki, Shingo, Kasai, Kiyoto, Mimura, Masaru, Pu, Shenghong, Noda, Takamasa, Niwa, Shin-ichi, Okazaki, Yuji
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.01.2014; Elsevier Limited
• Subjects: Acoustic Stimulation; Adult; Age; Algorithms; Biomarkers; Bipolar disorder; Bipolar Disorder - diagnosis; Bipolar Disorder - pathology; Brain Mapping; Brain research; Cerebrovascular Circulation - physiology; Children & youth; Data Interpretation, Statistical; Depressive Disorder - diagnosis; Depressive Disorder - pathology; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - pathology; Depressive state; Diagnosis, Differential; Differential diagnosis; Disease; Female; Functional Neuroimaging - methods; Hemodynamics - physiology; Hemoglobins - analysis; Hemoglobins - metabolism; Humans; Male; Medical imaging; Mental depression; Middle Aged; Mortality; Near-infrared spectroscopy (NIRS); Neuroimaging; Neurology; Neuropsychological Tests; Prefrontal Cortex - pathology; Psychiatric disorder; Psychiatric Status Rating Scales; Reproducibility of Results; ROC Curve; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - pathology; Spectroscopy, Near-Infrared - methods; Studies; Temporal Lobe - pathology; Neuroimaging; Near-infrared spectroscopy (NIRS); Differential diagnosis; Depressive state; Psychiatric disorder

A serious problem in psychiatric practice is the lack of specific, objective biomarker-based assessments to guide diagnosis and treatment. The use of such biomarkers could assist clinicians in establishing differential diagnosis, which may improve specific individualised treatment. This multi-site s...