Predictive and Prognostic Analysis of PIK3CA Mutation in Stage III Colon Cancer Intergroup Trial - Ogino, Shuji; Liao, Xiaoyun; Imamura, Yu; Yamauchi, Mai; McCleary, Nadine J.; Ng, Kimmie; Niedzwiecki, Donna; Saltz, Leonard B.; Mayer, Robert J.; Whittom, Renaud; Hantel, Alexander; Benson, Al B.; et al. (JNCI : Journal of the National Cancer Institute, 2013)
Keywords: Adult; Aged; Antineoplastic agents; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biological and medical sciences; Camptothecin - administration & dosage; Camptothecin - analogs & derivatives; Chemotherapy; Chemotherapy, Adjuvant; Class I Phosphatidylinositol 3-Kinases; Clinical outcomes; Colonic Neoplasms - drug therapy; Colonic Neoplasms - genetics; Colonic Neoplasms - pathology; Colonic Neoplasms - surgery; Colorectal cancer; Disease-Free Survival; Female; Fluorouracil - administration & dosage; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Kaplan-Meier Estimate; Leucovorin - administration & dosage; Male; Medical sciences; Microsatellite Instability; Middle Aged; Multivariate Analysis; Mutation; Neoplasm Staging; Oncology; Pharmacology. Drug treatments; Phosphatidylinositol 3-Kinases - genetics; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Proto-Oncogene Proteins - genetics; Proto-Oncogene Proteins B-raf - genetics; Proto-Oncogene Proteins p21(ras); ras Proteins - genetics; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Tumors; Antineoplastic agent; Relapse; Prognosis; Adjuvant treatment; Calcium folinate; Isomerases; Colon cancer; Cancerology; Genetics; Intestinal disease; Topoisomerase I inhibitor; Fluorouracil; Camptothecin derivatives; Human; Drug combination; Enzyme; Fluoropyrimidine derivatives; Transferases; Treatment efficiency; DNA topoisomerase; Enzyme inhibitor; Malignant tumor; Thymidylate synthase; Survival; 1-Phosphatidylinositol 3-kinase; Colonic disease; Irinotecan; Chemotherapy; Treatment; Antimetabolic; Methyltransferases; Pyrimidine derivatives; Digestive diseases; Locally advanced stage; Mutation; Cancer