Half-life extension using serum albumin-binding DARPin® domains - Steiner, Daniel; Merz, Frieder W; Sonderegger, Ivo; Gulotti-Georgieva, Maya; Villemagne, Denis; Phillips, Douglas J; Forrer, Patrik; Stumpp, Michael T; Zitt, Christof; Binz, H Kaspar (Protein engineering, design and selection, 2017)
Keywords: Animals; Ankyrin Repeat; Cloning, Molecular; Escherichia coli - genetics; Escherichia coli - metabolism; Gene Expression; Genetic Vectors - chemistry; Genetic Vectors - metabolism; Half-Life; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Protein Binding; Protein Stability; Recombinant Fusion Proteins - biosynthesis; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - pharmacokinetics; Serum Albumin - genetics; Serum Albumin - metabolism; pharmacokinetics; serum albumin; half-life; designed ankyrin repeat protein