Laundry detergents and detergent residue after rinsing directly disrupt tight junction barrier integrity in human bronchial epithelial cells - Wang, Ming; Tan, Ge; Eljaszewicz, Andrzej; Meng, Yifan; Wawrzyniak, Paulina; Acharya, Swati; Altunbulakli, Can; Westermann, Patrick; Dreher, Anita; Yan, Liying; Wang, Chengshuo; Akdis, Mubeccel; et al. (Journal of allergy and clinical immunology, 2019)
Keywords: Alarmins - genetics; Alarmins - metabolism; Allergies; Alveolar Epithelial Cells - metabolism; Alveolar Epithelial Cells - pathology; Apoptosis; Asthma; Asthma - metabolism; barrier function; Bronchi - pathology; bronchial epithelial cells; Cell adhesion; Cell adhesion & migration; Cell culture; Cell size; Cells, Cultured; Chromatin; Chronic obstructive pulmonary disease; Cytotoxicity; Deoxyribonucleic acid; Detergent industry; Detergents; Detergents - metabolism; DNA; DNA methylation; DNA sequencing; Electric Impedance; epigenome; Epithelial cells; Gene expression; Gene Expression Regulation; Health care; High-Throughput Nucleotide Sequencing; Households; Humans; L-Lactate dehydrogenase; L-Lactate Dehydrogenase - metabolism; Lactic acid; Laundry; Laundry detergent; Lipid Metabolism; Lung diseases; Metabolism; Next-generation sequencing; Obstructive lung disease; Public health; Ribonucleic acid; rinse residue; RNA; Studies; Surfactants; tight junction; Tight Junctions - metabolism; Tight Junctions - pathology; transcriptome; Transposase; Switzerland; TER; bronchial epithelial cells; SDBS; transcriptome; Laundry detergent; ATAC-seq; BP; LDH; FITC; RNA-seq; rinse residue; barrier function; tight junction; epigenome; TSLP; DMP; DEG; GO; asthma; ZO-1; UPLC; TJ; HBEC; ALI; chronic obstructive pulmonary disease; COPD