Detectable serum cardiac troponin T as a marker of poor prognosis among patients with chronic precapillary pulmonary hypertension

• Published in: Circulation (New York, N.Y.) Vol. 108; no. 7; pp. 844 - 848
• Main Authors: Torbicki, Adam, Kurzyna, Marcin, Kuca, Paweł, Fijałkowska, Anna, Sikora, Jarosław, Florczyk, Michał, Pruszczyk, Piotr, Burakowski, Janusz, Wawrzyńska, Lilianna
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 19.08.2003
• Subjects: Adult; Biomarkers - blood; Capillaries - physiopathology; Chronic Disease; Disease Progression; Echocardiography; Exercise Tolerance; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Pulmonary - blood; Hypertension, Pulmonary - diagnosis; Hypertension, Pulmonary - physiopathology; Lung - blood supply; Male; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Reproducibility of Results; Survival Rate; Troponin T - blood

Right ventricular failure is a leading cause of death in patients with chronic pulmonary hypertension (PH). We checked whether detection of cardiac troponin T (cTnT), a specific marker of myocyte injury, could be useful in prognostic stratification of those patients. Initial evaluation of 56 clinica...