Evidence for Borna disease virus infection in neuropsychiatric patients in three western China provinces

• Published in: European journal of clinical microbiology & infectious diseases Vol. 33; no. 4; pp. 621 - 627
• Main Authors: Zhang, L., Xu, M.-M., Zeng, L., Liu, S., Liu, X., Wang, X., Li, D., Huang, R.-Z., Zhao, L.-B., Zhan, Q.-L., Zhu, D., Zhang, Y.-Y., Xu, P., Xie, P.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2014; Springer; Springer Nature B.V
• Subjects: Adult; Antibodies; Antibodies, Viral - blood; Antibodies, Viral - cerebrospinal fluid; Autoimmune diseases; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Borna Disease - blood; Borna Disease - cerebrospinal fluid; Borna Disease - epidemiology; Borna Disease - virology; Borna disease virus; Borna disease virus - isolation & purification; China; Chronic fatigue syndrome; Disease; Emotional disorders; Encephalitis; Enzyme-Linked Immunosorbent Assay; Enzymes; Fatigue Syndrome, Chronic - blood; Fatigue Syndrome, Chronic - cerebrospinal fluid; Fatigue Syndrome, Chronic - epidemiology; Fatigue Syndrome, Chronic - virology; Female; Genomes; Hospitals; Humans; Infections; Infectious diseases; Internal Medicine; Male; Medical Microbiology; Medical sciences; Mental depression; Mental disorders; Middle Aged; Mood disorders; Multiple sclerosis; Nervous System Diseases - blood; Nervous System Diseases - cerebrospinal fluid; Nervous System Diseases - epidemiology; Nervous System Diseases - virology; Neurology; Neurosciences; Parkinson's disease; Polymerase chain reaction; Primates; RNA, Viral - blood; Schizophrenia; Schizophrenia - blood; Schizophrenia - cerebrospinal fluid; Schizophrenia - epidemiology; Schizophrenia - virology; Asia; China; Chronic Fatigue Syndrome Patient; Viral Encephalitis; Chronic Fatigue Syndrome; Cerebral Spinal Fluid; Major Depressive Disorder; Bornavirus; Virus; Human; Infection; Mononegavirales; Microbiology; Borna disease virus; Bornaviridae

Borna disease virus (BDV) is a non-cytolytic, neurotropic RNA virus that can infect a wide variety of vertebrate species from birds and primates to humans. Several studies have been carried out to investigate whether BDV is associated with neuropsychiatric diseases. However, this association is stil...