Food Nutrients and Bioactive Compounds for Managing Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comprehensive Review

• Published in: Nutrients Vol. 17; no. 13; p. 2211
• Main Authors: Dungubat, Erdenetsogt, Fujikura, Kohei, Kuroda, Masahiko, Fukusato, Toshio, Takahashi, Yoshihisa
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.07.2025; MDPI
• Subjects: Adipocytes; Amino acids; Caffeine; Carbohydrates; Clinical trials; Development and progression; Dextrose; Diet; Fatty Liver - diet therapy; Fructose; Glucose; Health aspects; Humans; Inflammation; Insulin; Insulin resistance; Lipids; Liver diseases; Medical research; Medicine, Experimental; Metabolic Diseases - complications; Metabolism; Micronutrients - administration & dosage; Non-alcoholic Fatty Liver Disease - diet therapy; Nutrients; Nutrients - administration & dosage; Oils & fats; Oxidative stress; Pathogenesis; Pathophysiology; Physiological aspects; Phytochemicals; Polyamines; Polyphenols; Polyunsaturated fatty acids; Processed foods; Proteins; Review; Saturated fatty acids; Trans fats; Trans fatty acids; Tumor necrosis factor-TNF; Type 2 diabetes; liver fibrosis; nutrition; fatty acid; polyphenol; zinc; metabolic dysfunction-associated steatohepatitis; metabolic dysfunction-associated steatotic liver disease; vitamin; dietary intervention

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), are growing global health concerns. However, pharmacological therapies for MASLD/MASH have not yet been established. Dietary interventions and their bio...