Structural and molecular analysis of the cancer prostate cell line PC3: Oocyte zona pellucida glycoproteins

• Published in: Tissue & cell Vol. 55; pp. 91 - 106
• Main Authors: Costa, Jéssica, Pereira, Rute, Oliveira, Jorge, Alves, Ângela, Marques-Magalhães, Ângela, Frutuoso, Amaro, Leal, Carla, Barros, Nuno, Fernandes, Rui, Queiroz Almeida, Diogo, Barreiro, Márcia, Barros, Alberto, Sousa, Mário, Sá, Rosália
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.12.2018; Elsevier Science Ltd
• Subjects: Adenocarcinoma; Cell Aggregation - physiology; Electron microscopy; Gene expression; Glycoproteins; Humans; Immunocytochemistry; Immunohistochemistry; Male; Oocytes - metabolism; Pavements; PC-3 Cells - cytology; PC3 cell line; Prostate - metabolism; Prostate - pathology; Prostate cancer; Prostate carcinoma; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Protein Processing, Post-Translational - physiology; Proteins; Real time PCR; Scanning electron microscopy; Ultrastructure; Zona pellucida; Zona pellucida glycoproteins; Zona Pellucida Glycoproteins - metabolism; Real time PCR; Electron microscopy; Immunocytochemistry; Zona pellucida glycoproteins; Prostate cancer; PC3 cell line

•PC3 cell line demonstrates two types of grow, adherent and in suspension.•Cells from each type of growing pattern present different ultrastructure.•Zona pellucida proteins expression was found on both prostate cancer and PC3 cells.•Pavement-cells (adherent) have a higher expression of ZP1, ZP3 and...