Gemcitabine delivered by fucoidan/chitosan nanoparticles presents increased toxicity over human breast cancer cells - Oliveira, Catarina; Neves, Nuno M; Reis, Rui L; Martins, Albino; Silva, Tiago H (Nanomedicine (London, England), 2018)
Keywords: Antineoplastic Agents - administration & dosage; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Breast cancer; breast cancer cells; Breast Neoplasms - metabolism; Cancer therapies; Cell Line; Cell Line, Tumor; Cell Survival - drug effects; chitosan; Chitosan - chemistry; Cytotoxicity; Deoxycytidine - administration & dosage; Deoxycytidine - analogs & derivatives; Deoxycytidine - chemistry; Deoxycytidine - pharmacology; Drug delivery systems; Drug Delivery Systems - methods; drug-delivery system; Drugs; endothelial cells; Endothelial Cells - drug effects; fucoidan; gemcitabine; Humans; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Nanoparticles - chemistry; Nanoparticles - ultrastructure; polyelectrolyte complexation; Polymers; Polymers - chemistry; Polysaccharides - chemistry; United Kingdom--UK; United States--US; breast cancer cells; chitosan; endothelial cells; nanoparticles; drug-delivery system; gemcitabine; fucoidan; polyelectrolyte complexation