TB Meningitis in HIV-Positive Patients in Europe and Argentina: Clinical Outcome and Factors Associated with Mortality

• Published in: BioMed research international Vol. 2013; pp. 373601 - 9
• Main Authors: Efsen, Anne Marie W., Panteleev, Alexander M., Grint, Daniel, Podlekareva, Daria N., Vassilenko, Anna, Rakhmanova, Aza, Zeltina, Indra, Losso, Marcelo H., Miller, Robert F., Girardi, Enrico, Caylá, Joan, Post, Frank A., Miro, Jose M., Bruyand, Mathias, Furrer, Hansjakob, Obel, Niels, Lundgren, Jens D., Mocroft, Amanda, Kirk, Ole, Study Group, HIV/TB
• Format: Journal Article
• Language: English
• Published: United States Hindawi Publishing Corporation 01.01.2013; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Acquired immune deficiency syndrome; Adult; AIDS; Argentina; CD4 Lymphocyte Count; Colleges & universities; Drug therapy; Europe; Female; HIV; HIV - isolation & purification; HIV - pathogenicity; HIV Infections - complications; HIV Infections - mortality; HIV Infections - pathology; HIV Infections - therapy; HIV Infections - virology; HIV patients; Hospitals; Human immunodeficiency virus; Humans; Kaplan-Meier Estimate; Male; Medical research; Medicine, Experimental; Meningitis; Mortality; Patient outcomes; Risk Factors; Treatment Outcome; Tuberculosis; Tuberculosis, Meningeal - complications; Tuberculosis, Meningeal - mortality; Tuberculosis, Meningeal - pathology; Tuberculosis, Meningeal - therapy; Tuberculosis, Meningeal - virology; Argentina; Europe; Latvia

Objectives. The study aimed at describing characteristics and outcome of tuberculous meningitis (TBM) in HIV-positive patients and comparing these parameters with those of extrapulmonary TB (TBEP) and pulmonary TB (TBP). Methods. Kaplan-Meier estimation and Poisson regression models were used to ass...