Impact of Sinus Surgery on Pseudomonal Airway Colonization, Bronchiolitis Obliterans Syndrome and Survival in Cystic Fibrosis Lung Transplant Recipients

• Published in: Respiration Vol. 86; no. 1; pp. 25 - 31
• Main Authors: Vital, Domenic, Hofer, Markus, Benden, Christian, Holzmann, David, Boehler, Annette
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.01.2013
• Subjects: Adult; Bronchiolitis Obliterans - complications; Bronchoalveolar Lavage Fluid - microbiology; Clinical Investigations; Cystic fibrosis; Cystic Fibrosis - complications; Cystic Fibrosis - microbiology; Cystic Fibrosis - surgery; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lung Transplantation - methods; Lungs; Male; Nasal Lavage - methods; Paranasal Sinuses - surgery; Proportional Hazards Models; Pseudomonas Infections - complications; Retrospective Studies; Survival analysis; Transplants & implants; Treatment Outcome; Cystic fibrosis; Bronchiolitis obliterans syndrome; Survival after lung transplantation; Lung transplantation; Paranasal sinus surgery; Pseudomonal airway colonization

Background: Lung transplantation (LTx) is a therapy for patients with cystic fibrosis (CF) end-stage lung disease. Pseudomonal airway colonization (PAC) is common in CF. Objectives: We investigated the influence of post-transplant sinus surgery and daily nasal douching on PAC after LTx and the influ...