A Systematic Review of the Valproic-Acid-Induced Rodent Model of Autism

• Published in: Developmental neuroscience Vol. 42; no. 1; p. 12
• Main Authors: Chaliha, Devahuti, Albrecht, Matthew, Vaccarezza, Mauro, Takechi, Ryu, Lam, Virginie, Al-Salami, Hani, Mamo, John
• Format: Journal Article
• Language: English
• Published: Switzerland 2020
• Subjects: Autism; Behaviour; Rodent; Valproic acid

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment. Unfortunately, few pharmacological treatments exist to alleviate these socio-behavioural impairments. Prenatal administration of...