Comparative analysis of Helicobacter DNAs and biliary pathology in patients with and without hepatobiliary cancer

• Published in: Carcinogenesis (New York) Vol. 23; no. 11; pp. 1927 - 1932
• Main Authors: Fukuda, Kenzo, Kuroki, Tamotsu, Tajima, Yoshitsugu, Tsuneoka, Noritsugu, Kitajima, Tomoo, Matsuzaki, Sumihiro, Furui, Junichiro, Kanematsu, Takashi
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.11.2002; Oxford Publishing Limited (England)
• Subjects: Adenoma - chemistry; Adenoma - microbiology; Adenoma - pathology; Adult; Aged; Aged, 80 and over; Ampulla of Vater; Antigens, Neoplasm - analysis; Bile Duct Neoplasms - chemistry; Bile Duct Neoplasms - microbiology; Bile Duct Neoplasms - pathology; Biliary Tract Neoplasms - chemistry; Biliary Tract Neoplasms - microbiology; Biliary Tract Neoplasms - pathology; Biological and medical sciences; Biomarkers; Carcinoma - chemistry; Carcinoma - microbiology; Carcinoma - pathology; Cell Cycle; Cholelithiasis - metabolism; Cholelithiasis - microbiology; Common Bile Duct Neoplasms - chemistry; Common Bile Duct Neoplasms - microbiology; Common Bile Duct Neoplasms - pathology; DNA, Bacterial - analysis; EGF; epidermal growth factor; Female; Gallbladder Neoplasms - chemistry; Gallbladder Neoplasms - microbiology; Gallbladder Neoplasms - pathology; Gastroenterology. Liver. Pancreas. Abdomen; Helicobacter - genetics; Helicobacter - isolation & purification; Helicobacter - pathogenicity; Helicobacter pylori - genetics; Helicobacter pylori - isolation & purification; Helicobacter pylori - pathogenicity; Humans; Liver Neoplasms - chemistry; Liver Neoplasms - microbiology; Liver Neoplasms - pathology; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; Organ Specificity; PCNA; PCR; Polymerase Chain Reaction; proliferating cell nuclear antigen; Proliferating Cell Nuclear Antigen - analysis; Tumors; Human; Cell proliferation; Spirillales; Helicobacter; Pathogenesis; Tumoral tissue; Spirillaceae; Hepatic disease; Malignant tumor; Hepatobiliary disease; Biliary tract disease; Carcinogenesis; Hepatobiliary; DNA; Digestive diseases; Bacteria; Kinetics; Comparative study; Bile

Several Helicobacter species have recently been isolated from the bile and hepatobiliary systems of murine species, and are well recognized as a pathogen of the hepatobiliary disorder. This study was planned to investigate whether Helicobacter species possess a causative potential for human hepatobi...