Response of peripheral blood basophils in subjects with chronic spontaneous urticaria during treatment with omalizumab - MacGlashan, Donald; Saini, Sarbjit; Schroeder, John T. (Journal of allergy and clinical immunology, 2021)
Keywords: allergy; Anti-Allergic Agents - administration & dosage; Anti-Allergic Agents - adverse effects; Anti-Allergic Agents - therapeutic use; Antibodies; Asthma; auto-antibodies; Autoantibodies; Autoantibodies - blood; Autoantibodies - immunology; Basopenia; basophil; Basophils - drug effects; Basophils - immunology; Basophils - metabolism; Biomarkers; Chronic Urticaria - diagnosis; Chronic Urticaria - drug therapy; Chronic Urticaria - immunology; Food allergies; Genotype & phenotype; Histamine; Histamine Release; Human; Humans; Immunoglobulin E; Immunoglobulin E - immunology; Kinases; Laboratories; Leukocyte Count; Leukocytes (basophilic); Monoclonal antibodies; Omalizumab - administration & dosage; Omalizumab - adverse effects; Omalizumab - therapeutic use; Patients; Peripheral blood; Phenotypes; Protein-tyrosine kinase; Receptors, IgE - metabolism; Signal Transduction; Spleen; Syk Kinase - metabolism; Syk protein; Treatment Outcome; Urticaria; Human; CSU-NR; CSU; fMLP; SYK; signal transduction; PMA; uFcεRI; allergy; HR; basophil; pDC; auto-antibodies; MFI; PBB; AS; phenotypes; PE; BTK; EC50; tFcεRI; CSU-R