Development and application of microfluidic sweat detection technology in mental health monitoring

Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space missions. Traditional wearable sensors often focus on physiological indicators such as heart rate, but microfluidic wearable sensors of...

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Published inView (Beijing, China) Vol. 6; no. 3
Main Authors Zhao, Danni, Chen, Ran, Jiang, Shuyue, Xie, Weiwei, Zhang, Kaihuan, Zhao, Jianlong, Feng, Shilun, Bian, Shengtai
Format Journal Article
LanguageEnglish
Published Beijing John Wiley & Sons, Inc 01.06.2025
Wiley
Subjects
Accuracy
Biomarkers
Electrodes
Exocrine glands
Heat
Iontophoresis
Medical research
Mental health
mental monitoring
Methods
microfluidics
Physiology
Sensors
Skin
Sports injuries
Stress
sweat
Sweating
Temperature
Wearable computers
wearable sensor
Well being
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Abstract Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space missions. Traditional wearable sensors often focus on physiological indicators such as heart rate, but microfluidic wearable sensors offer a promising alternative by enabling precise, quantitative analysis of sweat biomarkers. This review explores recent advancements in microfluidic wearable sensors for mental health monitoring, highlighting their ability to analyze biomarkers such as stress hormones, dopamine, and catecholamines. We discuss the development, application methods, and challenges of these sensors, as well as their future prospects in mental health monitoring. In this review, the authors emphasize the potential of microfluidic sweat detection technology in the field of mental health monitoring. The work explores the intricate relationship between psychological disorders, such as depression and anxiety, and their physiological impact, emphasizing how these conditions can influence systemic health. Furthermore, the study discusses key sweat‐associated biomarkers, including serotonin, cortisol, dopamine, glucose and lactate, which have been linked to mental health status. The review also provides an in‐depth analysis of advanced microfluidic sensor technologies, such as electrochemical sensors, nanobiosensors, enzyme‐based electrodes and colorimetric biosensors, showcasing their application in real‐time, non‐invasive mental health assessment. Additionally, this study addresses the challenges, opportunities, and future perspectives in integrating sweat biomarker detection into routine mental health diagnostics, filling a critical gap in the current literature.
AbstractList Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space missions. Traditional wearable sensors often focus on physiological indicators such as heart rate, but microfluidic wearable sensors offer a promising alternative by enabling precise, quantitative analysis of sweat biomarkers. This review explores recent advancements in microfluidic wearable sensors for mental health monitoring, highlighting their ability to analyze biomarkers such as stress hormones, dopamine, and catecholamines. We discuss the development, application methods, and challenges of these sensors, as well as their future prospects in mental health monitoring. In this review, the authors emphasize the potential of microfluidic sweat detection technology in the field of mental health monitoring. The work explores the intricate relationship between psychological disorders, such as depression and anxiety, and their physiological impact, emphasizing how these conditions can influence systemic health. Furthermore, the study discusses key sweat‐associated biomarkers, including serotonin, cortisol, dopamine, glucose and lactate, which have been linked to mental health status. The review also provides an in‐depth analysis of advanced microfluidic sensor technologies, such as electrochemical sensors, nanobiosensors, enzyme‐based electrodes and colorimetric biosensors, showcasing their application in real‐time, non‐invasive mental health assessment. Additionally, this study addresses the challenges, opportunities, and future perspectives in integrating sweat biomarker detection into routine mental health diagnostics, filling a critical gap in the current literature.
Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space missions. Traditional wearable sensors often focus on physiological indicators such as heart rate, but microfluidic wearable sensors offer a promising alternative by enabling precise, quantitative analysis of sweat biomarkers. This review explores recent advancements in microfluidic wearable sensors for mental health monitoring, highlighting their ability to analyze biomarkers such as stress hormones, dopamine, and catecholamines. We discuss the development, application methods, and challenges of these sensors, as well as their future prospects in mental health monitoring.
Abstract Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space missions. Traditional wearable sensors often focus on physiological indicators such as heart rate, but microfluidic wearable sensors offer a promising alternative by enabling precise, quantitative analysis of sweat biomarkers. This review explores recent advancements in microfluidic wearable sensors for mental health monitoring, highlighting their ability to analyze biomarkers such as stress hormones, dopamine, and catecholamines. We discuss the development, application methods, and challenges of these sensors, as well as their future prospects in mental health monitoring.
Author Feng, Shilun
Jiang, Shuyue
Zhang, Kaihuan
Chen, Ran
Bian, Shengtai
Xie, Weiwei
Zhao, Danni
Zhao, Jianlong
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Snippet Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving and space...
Abstract Mental health significantly affects individuals' thoughts and behaviors, making its monitoring crucial in high‐stakes environments like truck driving...
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SubjectTerms Accuracy
Biomarkers
Electrodes
Exocrine glands
Heat
Iontophoresis
Medical research
Mental health
mental monitoring
Methods
microfluidics
Physiology
Sensors
Skin
Sports injuries
Stress
sweat
Sweating
Temperature
Wearable computers
wearable sensor
Well being
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Title Development and application of microfluidic sweat detection technology in mental health monitoring
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