Mucopolysaccharidosis type I (Hurler syndrome) and anesthesia: the impact of bone marrow transplantation, enzyme replacement therapy, and fiberoptic intubation on airway management

• Published in: Pediatric anesthesia Vol. 22; no. 8; pp. 745 - 751
• Main Authors: Kirkpatrick, Katherine, Ellwood, James, Walker, Robert W. M.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.2012; Wiley Subscription Services, Inc
• Subjects: Adolescent; Airway management; Airway Management - methods; Anesthesia; Bone marrow; Bone Marrow Transplantation - methods; Child; Child, Preschool; difficult airway; Enzyme Replacement Therapy; Female; Fiber Optic Technology; Humans; Hurler syndrome; Infant; Intubation; Laryngeal Masks; Laryngoscopy; Male; mucopolysaccharidoses; Mucopolysaccharidosis I - physiopathology; Mucopolysaccharidosis I - surgery; Mucopolysaccharidosis I - therapy; Patients; Retrospective Studies; Transplants & implants; Treatment Failure

Summary Aim:  To assess the effect of bone marrow transplantation (BMT), enzyme replacement therapy (ERT), and a fiberoptic endotracheal intubation technique in patients with mucopolysaccharidosis type I (MPS I, Hurler syndrome). Background:  The mucopolysaccharidoses are inherited metabolic conditi...