Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo

• Published in: Photodermatology, photoimmunology & photomedicine Vol. 22; no. 2; pp. 105 - 110
• Main Authors: Ibbotson, S. H., Jong, C., Lesar, A., Ferguson, J. S., Padgett, M., O'Dwyer, M., Barnetson, R., Ferguson, J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.04.2006; Blackwell
• Subjects: 5-aminolaevulinic acid (ALA); Adult; Aminolevulinic Acid - pharmacology; Biological and medical sciences; Dermatology; Diseases of the skin. Cosmetics; Female; Fluorescence; Humans; Male; Medical sciences; Middle Aged; photodynamic therapy (PDT); protoporphyrin IX (PpIX); Protoporphyrins - pharmacology; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Reference Values; Skin - drug effects; Human; 5-Aminolevulinic acid; In vivo; Photodynamic therapy; Protoporphyrin; Dermatology; 5-aminolaevulinic acid (ALA); Fluorescence; protoporphyrin IX (PpIX); Skin; photodynamic therapy (PDT); Experimental study

Background/Purpose: Topical photodynamic therapy (PDT) is increasingly being used to treat skin cancers. Knowledge of the detailed characteristics of 5‐aminolaevulinic acid (ALA)‐induced protoporphyrin IX (PpIX) fluorescence in diseased and normal skin is incomplete. Understanding the characteristic...