Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats

• Published in: Journal of biomedical materials research. Part B, Applied biomaterials Vol. 78B; no. 2; pp. 334 - 339
• Main Authors: Miguel, Fúlvio B., Cardoso, Ana Karina M. V., Barbosa Jr, Aryon A., Marcantonio Jr, Elcio, Goissis, Gilberto, Rosa, Fabiana P.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.08.2006
• Subjects: Animals; anionic collagen; Bone Regeneration; Bone Substitutes - adverse effects; Calcification, Physiologic; Collagen - adverse effects; Craniocerebral Trauma - therapy; critical size defect; Guided Tissue Regeneration - adverse effects; Male; Neovascularization, Physiologic; Rats; Rats, Wistar; Skull - injuries; Skull - pathology; three-dimensional matrix; Time Factors; tissue bioengineering

The osteogenic behavior of three‐dimensional collagenic and anionic matrices (M3DGA) implanted in critical bone defects of 8 mm diameter was morphologically assessed. The defects were performed in the calvaria of 48 adult male (Wistar) rats, and observed at days 15, 30, and 60. The animals were dist...