Omega‐3 Polyunsaturated Fatty Acids Inhibit IL‐17A Secretion through Decreased ICAM‐1 Expression in T Cells Co‐Cultured with Adipose‐Derived Stem Cells Harvested from Adipose Tissues of Obese Subjects - Chehimi, Marwa; Ward, Robert; Pestel, Julien; Robert, Maud; Pesenti, Sandra; Bendridi, Nadia; Michalski, Marie‐Caroline; Laville, Martine; Vidal, Hubert; Eljaafari, Assia (Molecular nutrition & food research, 2019)
Keywords: Adipocytes; Adipose tissue; Adipose Tissue - cytology; adipose tissue‐derived stem cells; alpha-linolenic acid; alpha-Linolenic Acid - pharmacology; Cell Aggregation - drug effects; coculture; Coculture Techniques; Docosahexaenoic acid; eicosapentaenoic acid; Fatty acids; Fatty Acids, Omega-3 - pharmacology; Helper cells; Humans; ICAM‐1; IL‐17A; Immune system; Inflammation; intercellular adhesion molecule-1; Intercellular Adhesion Molecule-1 - genetics; interleukin-17; Interleukin-17 - antagonists & inhibitors; Interleukin-17 - biosynthesis; interleukin-1beta; interleukin-6; Leukocytes (mononuclear); Linolenic acid; Lymphocytes T; Monocytes; obese adipose tissues; Obesity - metabolism; Omega 3 PUFA; omega-3 fatty acids; Oxygenase; Palmitic acid; Polyunsaturated fatty acids; secretion; STAT3 Transcription Factor - antagonists & inhibitors; Stem cells; Stem Cells - drug effects; Stem Cells - immunology; Stem Cells - physiology; T-lymphocytes; Th17 Cells - drug effects; Th17 Cells - immunology; Toll-like receptor 4; Toll-Like Receptor 4 - antagonists & inhibitors; Toll-like receptors; Transcription; tumor necrosis factor-alpha; Tumor necrosis factor-α; Omega 3 PUFA; obese adipose tissues; ICAM-1; IL-17A; adipose tissue-derived stem cells