The nsdC Gene Encoding a Putative C2H2-Type Transcription Factor Is a Key Activator of Sexual Development in Aspergillus nidulans

• Published in: Genetics (Austin) Vol. 182; no. 3; pp. 771 - 783
• Main Authors: Kim, Hye-Ryun, Chae, Keon-Sang, Han, Kap-Hoon, Han, Dong-Min
• Format: Journal Article
• Language: English
• Published: United States Genetics Soc America 01.07.2009; Genetics Society of America
• Subjects: Acetates - pharmacology; Amino Acid Sequence; Aspergillus nidulans - drug effects; Aspergillus nidulans - genetics; Aspergillus nidulans - physiology; Blotting, Northern; DNA-Binding Proteins - genetics; Fungal Proteins - genetics; Fungal Proteins - metabolism; Gene Expression Regulation, Developmental; Gene Expression Regulation, Fungal; Glucose - pharmacology; Glycerol - pharmacology; Introns - genetics; Investigations; Lactose - pharmacology; Molecular Sequence Data; Mutation; Mycelium - drug effects; Mycelium - genetics; Mycelium - growth & development; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; RNA, Messenger - genetics; RNA, Messenger - metabolism; Sequence Homology, Amino Acid; Spores, Fungal - growth & development; Time Factors; Transcription Factors - genetics; Transcription Factors - metabolism; Zinc Fingers

The formation of the Aspergillus nidulans fruiting body is affected by a number of genetic and environmental factors. Here, the nsdC (never in sexual development) gene-encoding a putative transcription factor carrying a novel type of zinc-finger DNA-binding domain consisting of two C(2)H(2)'s a...