Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults: Fourth edition
The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Sci...
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Published in | Cephalalgia Vol. 39; no. 6; pp. 687 - 710 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
London, England
SAGE Publications
01.05.2019
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Subjects | |
Online Access | Get full text |
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Abstract | The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks. |
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AbstractList | The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks. The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine . Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks. The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks.The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks. |
Author | Lipton, Richard B Goadsby, Peter J Silberstein, Stephen D Pozo-Rosich, Patricia Mandrekar, Jay Dodick, David W Ashina, Messoud Diener, Hans-Christoph Tassorelli, Cristina Becker, Werner J Ferrari, Michel D Wang, Shuu-Jiun |
AuthorAffiliation | 2 Headache Science Center, IRCCS Mondino Foundation, Pavia, Italy 4 Department of Neurology, Mayo Clinic, Phoenix, AZ, USA 8 Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada 11 National Institute for Health Research Wellcome Trust King's Clinical Research Facility, King's College London, London, England 5 Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA, USA 6 Montefiore Headache Center, Department of Neurology and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA 14 Neurological Institute, Taipei Veterans General Hospital and Brain Research Center, National Yang-Ming University, Taipei, Taiwan 3 Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy 7 Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Denmark 13 Headache & Craniofacial Pain Unit, Neurology Depar |
AuthorAffiliation_xml | – name: 7 Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Denmark – name: 2 Headache Science Center, IRCCS Mondino Foundation, Pavia, Italy – name: 6 Montefiore Headache Center, Department of Neurology and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA – name: 4 Department of Neurology, Mayo Clinic, Phoenix, AZ, USA – name: 5 Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA, USA – name: 9 Hotchkiss Brain Institute, University of Calgary, Calgary, Canada – name: 10 Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands – name: 12 Headache Research Group, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Barcelona, Spain – name: 11 National Institute for Health Research Wellcome Trust King's Clinical Research Facility, King's College London, London, England – name: 14 Neurological Institute, Taipei Veterans General Hospital and Brain Research Center, National Yang-Ming University, Taipei, Taiwan – name: 3 Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy – name: 15 Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA – name: 1 Department of Neurology, University Hospital Essen, Essen, Germany – name: 8 Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada – name: 13 Headache & Craniofacial Pain Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain |
Author_xml | – sequence: 1 givenname: Hans-Christoph surname: Diener fullname: Diener, Hans-Christoph email: hans.diener@uni-duisburg-essen.de – sequence: 2 givenname: Cristina surname: Tassorelli fullname: Tassorelli, Cristina – sequence: 3 givenname: David W surname: Dodick fullname: Dodick, David W – sequence: 4 givenname: Stephen D surname: Silberstein fullname: Silberstein, Stephen D – sequence: 5 givenname: Richard B surname: Lipton fullname: Lipton, Richard B – sequence: 6 givenname: Messoud surname: Ashina fullname: Ashina, Messoud – sequence: 7 givenname: Werner J surname: Becker fullname: Becker, Werner J – sequence: 8 givenname: Michel D surname: Ferrari fullname: Ferrari, Michel D – sequence: 9 givenname: Peter J orcidid: 0000-0003-3260-5904 surname: Goadsby fullname: Goadsby, Peter J – sequence: 10 givenname: Patricia surname: Pozo-Rosich fullname: Pozo-Rosich, Patricia – sequence: 11 givenname: Shuu-Jiun surname: Wang fullname: Wang, Shuu-Jiun – sequence: 12 givenname: Jay surname: Mandrekar fullname: Mandrekar, Jay |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30806518$$D View this record in MEDLINE/PubMed |
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Keywords | acute treatment of migraine attacks in adults controlled trials Guidelines |
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Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Instructional Material/Guideline-1 ObjectType-Feature-3 content type line 23 These authors contributed equally to this work. |
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Title | Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults: Fourth edition |
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