Feasibility of an acoustophoresis-based system for a high-throughput cell washing: application to bioproduction

• Published in: Cytotherapy (Oxford, England) Vol. 25; no. 8; pp. 891 - 899
• Main Authors: Sugier, Hugo R., Bellebon, Ludovic, Aider, Jean-Luc, Larghero, Jérôme, Peltzer, Juliette, Martinaud, Christophe
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.08.2023; Elsevier
• Subjects: Acoustics; acoustophoresis; Adipose Tissue; bioproduction; Biotechnology; cell washing; Cellular Biology; downstream processing; Engineering Sciences; Erythrocytes; Feasibility Studies; Life Sciences; Mesenchymal Stem Cells; mesenchymal stromal cells; transcriptomics; transcriptomics; bioproduction; cell washing; downstream processing; acoustophoresis; mesenchymal stromal cells; Mesenchymal Stromal Cells; Transcriptomics; Downstream processing; Acoustophoresis Bioproduction Cell washing Downstream processing Mesenchymal Stromal Cells Transcriptomics; Bioproduction; Acoustophoresis; Cell washing

These last decades have seen the emergence and development of cell-based therapies, notably those based on mesenchymal stromal cells (MSCs). The advancement of these promising treatments requires increasing the throughput of processed cell for industrialization in order to reduce production costs. A...