Bioconcentration, behavioral, and biochemical effects of the non-steroidal anti-inflammatory drug diclofenac in Daphnia magna

• Published in: Environmental science and pollution research international Vol. 26; no. 6; pp. 5704 - 5712
• Main Authors: Nkoom, Matthew, Lu, Guanghua, Liu, Jianchao, Dong, Huike, Yang, Haohan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2019; Springer Nature B.V
• Subjects: Acetylcholinesterase; Anti-inflammatory agents; antioxidant activity; Antioxidants; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Bioaccumulation; bioaccumulation factor; Biochemistry; Biological magnification; Catalase; Daphnia magna; Diclofenac; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental science; enzyme activity; Exposure; filtration; Glutathione; Glutathione reductase; Glutathione transferase; glutathione-disulfide reductase; Inflammation; Ingestion; Invertebrates; Malondialdehyde; nonsteroidal anti-inflammatory agents; Nonsteroidal anti-inflammatory drugs; Oxidative stress; Reactive oxygen species; Research Article; Superoxide dismutase; Toxicity; Waste Water Technology; Water Management; Water Pollution Control; Waterways; Oxidative stress; Biomarker; Feeding behavior; Bioconcentration; Diclofenac; Daphnia magna

The non-steroidal anti-inflammatory drug (NSAID) diclofenac is one of the most frequently studied as well as controversially discussed pharmaceutically active drug on the subject of its relevance to the environment. This study was conducted to assess the bioconcentration potential of diclofenac and...