Cationic peptides from peptic hydrolysates of rice endosperm protein exhibit antimicrobial, LPS-neutralizing, and angiogenic activities

• Published in: Peptides (New York, N.Y. : 1980) Vol. 97; pp. 70 - 78
• Main Authors: Taniguchi, Masayuki, Kawabe, Junya, Toyoda, Ryu, Namae, Toshiki, Ochiai, Akihito, Saitoh, Eiichi, Tanaka, Takaaki
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2017
• Subjects: Angiogenic peptides; Angiogenic Proteins - chemistry; Angiogenic Proteins - pharmacology; Animals; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Antifungal Agents - pharmacology; Antimicrobial Cationic Peptides - chemical synthesis; Antimicrobial Cationic Peptides - chemistry; Antimicrobial peptides; Bacteria - drug effects; Endosperm - chemistry; Fungi - drug effects; Hemolysis - drug effects; Human Umbilical Vein Endothelial Cells; Humans; Hydrolysates of rice endosperm proteins; Hydrolysis; Inhibitory Concentration 50; Lipopolysaccharides; LPS-neutralizing peptides; Multi-functional cationic peptides; Oryza - chemistry; Plant Proteins - chemistry; Multi-functional cationic peptides; Hydrolysates of rice endosperm proteins; Angiogenic peptides; LPS-neutralizing peptides; Antimicrobial peptides

•Peptides were fractionated from hydrolysates of rice endosperm protein by autofocusing.•Cationic peptides were purified by RP-HPLC and then identified by MALDI-TOF MS.•Of identified peptides, five cationic peptides exhibited dual or multiple functions.•Five peptides exhibited angiogenic and LPS-neu...