Antibody persistence for 3 years following two doses of tetravalent measles–mumps–rubella–varicella vaccine in healthy children

• Published in: European journal of pediatrics Vol. 171; no. 3; pp. 463 - 470
• Main Authors: Knuf, Markus, Zepp, Fred, Helm, Klaus, Maurer, Hartwig, Prieler, Albrecht, Kieninger-Baum, Dorothee, Douha, Martine, Willems, Paul
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.03.2012; Springer; Springer Nature B.V
• Subjects: Antibodies; Antibodies, Viral - blood; Biological and medical sciences; Chicken pox; Chickenpox - immunology; Chickenpox Vaccine - administration & dosage; Chickenpox Vaccine - immunology; Child, Preschool; Children; Combined vaccines; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Follow-Up Studies; General aspects; Herpesvirus 3, Human - immunology; Human viral diseases; Humans; Immunity; Immunization Schedule; Immunofluorescence; Immunogenicity; Infant; Infectious diseases; Measles; Measles - immunology; Measles virus - immunology; Measles-Mumps-Rubella Vaccine - administration & dosage; Measles-Mumps-Rubella Vaccine - immunology; Medical sciences; Medicine; Medicine & Public Health; Mumps; Mumps - immunology; Mumps virus - immunology; Original Paper; Pediatrics; Rubella; Rubella - immunology; Rubella virus - immunology; Vaccination; Vaccines; Vaccines, Combined; Varicella; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye; Belgium; Austria; Germany; Varicella; MMRV vaccine; Varicella vaccine; Mumps neutralization; Human; Pediatrics; Rubella; Skin disease; Antibody; Vaccination; Vaccine; Infection; Persistence; Prevention; Immunoprophylaxis; Viral disease; Measles; Mumps; Dose; Child; Neutralization

Two doses of a varicella-containing vaccine in healthy children <12 years are suggested to induce better protection than a single dose. Persistence of immunity against measles, mumps, rubella, and varicella as well as varicella breakthrough cases were assessed 3 years after two-dose measles, mump...