Next generation sequencing analysis of patients with familial cervical artery dissection

• Published in: European stroke journal Vol. 2; no. 2; pp. 137 - 143
• Main Authors: Grond-Ginsbach, Caspar, Brandt, Tobias, Kloss, Manja, Aksay, Suna Su, Lyrer, Philipp, Traenka, Christopher, Erhart, Philipp, Martin, Juan Jose, Altintas, Ayse, Siva, Aksel, de Freitas, Gabriel R, Thie, Andreas, Machetanz, Jochen, Baumgartner, Ralf W, Dichgans, Martin, Engelter, Stefan T
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.06.2017
• Subjects: Original s; Cervical artery dissection; non-benign single nucleotide variants; arterial connective tissue disorder

Background The cause of cervical artery dissection is not well understood. We test the hypothesis that mutations in genes associated with known arterial connective tissue disorders are enriched in patients with familial cervical artery dissection. Patients and methods Patient duos from nine pedigree...