Intraarticular Injection of a Cross-Linked Sodium Hyaluronate Combined with Triamcinolone Hexacetonide (Cingal) to Provide Symptomatic Relief of Osteoarthritis of the Knee: A Randomized, Double-Blind, Placebo-Controlled Multicenter Clinical Trial

• Published in: Cartilage Vol. 9; no. 3; pp. 276 - 283
• Main Authors: Hangody, Laszlo, Szody, Robert, Lukasik, Piotr, Zgadzaj, Wojciech, Lénárt, Endre, Dokoupilova, Eva, Bichovsk, Daniela, Berta, Agnes, Vasarhelyi, Gabor, Ficzere, Andrea, Hangody, György, Stevens, Gary, Szendroi, Miklos
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.07.2018
• Subjects: Aged; Anti-Inflammatory Agents - therapeutic use; Clinical Papers; Combined Modality Therapy - methods; Double-Blind Method; Female; Humans; Hyaluronic Acid - administration & dosage; Hyaluronic Acid - therapeutic use; Injections, Intra-Articular - methods; Knee Joint - drug effects; Knee Joint - pathology; Male; Middle Aged; Osteoarthritis, Knee - drug therapy; Treatment Outcome; Triamcinolone Acetonide - administration & dosage; Triamcinolone Acetonide - analogs & derivatives; Triamcinolone Acetonide - therapeutic use; Viscosupplements - therapeutic use; clinical trial; general; knee; joint involved; intraarticular delivery; osteoarthritis; diagnosis; therapeutic delivery

Objective: To evaluate the efficacy and safety of an intraarticular injection of Cingal (Anika Therapeutics, Inc., Bedford, MA) compared with Monovisc (Anika Therapeutics, Inc., Bedford, MA) or saline for the treatment of knee osteoarthritis. Design: This multicenter, double-blind, saline-controlled...