Human gut endogenous proteins as a potential source of angiotensin-I-converting enzyme (ACE-I)-, renin inhibitory and antioxidant peptides

• Published in: Peptides (New York, N.Y. : 1980) Vol. 76; pp. 30 - 44
• Main Authors: Dave, Lakshmi A., Hayes, Maria, Montoya, Carlos A., Rutherfurd, Shane M., Moughan, Paul J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2016
• Subjects: Angiotensin I converting enzyme (ACE-I) inhibition; Angiotensin-Converting Enzyme Inhibitors - isolation & purification; Animals; antimicrobial peptides; Antioxidant peptides; Antioxidants; Antioxidants - isolation & purification; Bioactive peptides; Biocompatibility; breast milk; Classification of bioactive peptides; Cryptome proteins; dietary protein; Digestion; digestive enzymes; Enzymes; epithelial cells; Gastrointestinal endogenous proteins; Gastrointestinal Microbiome; gastrointestinal system; Gastrointestinal tract; Gastrointestinal Tract - chemistry; Gastrointestinal Tract - microbiology; Gastrointestinal Tract - secretion; Gut non-dietary proteins; hormones; Human; Humans; immunity; intestinal microorganisms; mucins; Peptides; Peptides - isolation & purification; Peptides - secretion; Peptidyl-Dipeptidase A; protein secretion; Proteins; Renin; serum albumin; ExBP; NOD; QS; ENL; DPP-IV; GALT; RAS; Gut non-dietary proteins; Antioxidant peptides; Gastrointestinal tract; TEnBP; ENS; ACE-I; Cryptome proteins; Gastrointestinal endogenous proteins; Classification of bioactive peptides; Angiotensin I converting enzyme (ACE-I) inhibition; GIT; GEP; Renin; Bioactive peptides

•The potential of gastrointestinal endogenous proteins (GEP) as a source of exogenous bioactive peptides in the gut lumen.•The major GEP that may give rise to bioactive peptides.•Clear classification of bioactive peptides based on their site of generation.•Brief description of the importance of bioa...