A comparison of treatment results for recurrent malignant gliomas

• Published in: Cancer treatment reviews Vol. 26; no. 6; pp. 397 - 409
• Main Authors: Nieder, C., Grosu, A.L., Molls, M.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.12.2000; Elsevier
• Subjects: Adult; Antineoplastic agents; Antineoplastic Agents - therapeutic use; Biological and medical sciences; Brain Neoplasms - pathology; Brain Neoplasms - therapy; Clinical Trials as Topic; Combined Modality Therapy; Female; General aspects; Glioma - pathology; Glioma - therapy; Humans; Male; Malignant gliomas, high-grade gliomas, recurrent gliomas, therapy, surgery, radiotherapy, chemotherapy; Medical sciences; Middle Aged; Neoplasm Recurrence, Local; Pharmacology. Drug treatments; Quality of Life; Radiosurgery - adverse effects; Radiotherapy - adverse effects; Survival Analysis; Treatment Outcome; Malignant gliomas, high-grade gliomas, recurrent gliomas, therapy, surgery, radiotherapy, chemotherapy; Antineoplastic agent; Human; Nervous system diseases; Relapse; Prognosis; Treatment efficiency; Malignant tumor; Review; Radiotherapy; Survival; Malignant glioma; Chemotherapy; Treatment; Surgery; Central nervous system disease; Clinical trial; Salvage treatment; Predictive factor; Comparative study

Retreatment of malignant gliomas may be performed with palliative intent after careful consideration of the risks and benefits, and with special regards to iatrogenic neurotoxicity and quality of life (QOL). This review compares studies of several retreatment strategies (published between 1987 and 2...