Assessment of vascular stiffness in the internal carotid artery proximal to the carotid canal in Alzheimer’s disease using pulse wave velocity from low rank reconstructed 4D flow MRI

• Published in: Journal of cerebral blood flow and metabolism Vol. 41; no. 2; pp. 298 - 311
• Main Authors: Rivera-Rivera, Leonardo A, Cody, Karly A, Eisenmenger, Laura, Cary, Paul, Rowley, Howard A, Carlsson, Cynthia M, Johnson, Sterling C, Johnson, Kevin M
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.02.2021
• Subjects: Aged; Alzheimer Disease - pathology; Blood Flow Velocity - physiology; Carotid Artery, Internal - pathology; Female; Hemodynamics; Humans; Magnetic Resonance Imaging - methods; Male; Original; Pulse Wave Analysis - methods; Retrospective Studies; Vascular Stiffness - physiology; arterial stiffness; 4D flow MRI; Alzheimer’s disease; hemodynamics; PWV

Clinical evidence shows vascular factors may co-occur and complicate the expression of Alzheimer’s disease (AD); yet, the pathologic mechanisms and involvement of different compartments of the vascular network are not well understood. Diseases such as arteriosclerosis diminish vascular compliance an...