Hypercapnia increases brain viscoelasticity

• Published in: Journal of cerebral blood flow and metabolism Vol. 39; no. 12; pp. 2445 - 2455
• Main Authors: Hetzer, Stefan, Dittmann, Florian, Bormann, Karl, Hirsch, Sebastian, Lipp, Axel, Wang, Danny JJ, Braun, Jürgen, Sack, Ingolf
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.12.2019
• Subjects: Adult; Cerebrovascular Circulation; Elasticity; Elasticity Imaging Techniques; Gray Matter - blood supply; Gray Matter - physiopathology; Humans; Hypercapnia - diagnostic imaging; Hypercapnia - physiopathology; Male; Models, Cardiovascular; Original; Viscosity; Elasticity; perfusion; Fåhræus–Lindqvist; vasodilation; hypercapnia

Brain function, the brain’s metabolic activity, cerebral blood flow (CBF), and intracranial pressure are intimately linked within the tightly autoregulated regime of intracranial physiology in which the role of tissue viscoelasticity remains elusive. We applied multifrequency magnetic resonance elas...