Tissue Factor Structure and Function

• Published in: Scientifica (Cairo) Vol. 2012; no. 2012; pp. 1 - 15
• Main Author: Butenas, Saulius
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Puplishing Corporation 01.01.2012; Hindawi Publishing Corporation; Wiley
• Subjects: Review

Tissue factor (TF) is an integral membrane protein that is essential to life. It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and thrombosis. With a vascular injury, TF becomes exposed to blood and binds plasma factor VIIa, and the resulting...